Special

MmuEX6078789 @ mm10

Exon Skipping

Gene
Description
vav 1 oncogene [Source:MGI Symbol;Acc:MGI:98923]
Coordinates
chr17:57296700-57297341:+
Coord C1 exon
chr17:57296700-57296768
Coord A exon
chr17:57297049-57297157
Coord C2 exon
chr17:57297246-57297341
Length
109 bp
Sequences
Splice sites
3' ss Seq
GGCCTGAATCTGTCCCCTAGTGA
3' ss Score
5.86
5' ss Seq
CCAGTGAGT
5' ss Score
8.28
Exon sequences
Seq C1 exon
GCCCTTCCCAACAGAGGACAGCGCTCTGAACGACGAAGATATTTACAGTGGCCTTTCAGACCAGATTGA
Seq A exon
TGACACCGCAGAGGAAGACGAGGACCTTTATGACTGCGTGGAAAATGAGGAGGCAGAGGGGGACGAGATCTACGAGGACCTAATGCGCTTGGAGTCGGTGCCTACGCCA
Seq C2 exon
CCCAAGATGACAGAGTATGATAAGCGCTGCTGCTGCCTGCGGGAGATCCAGCAGACGGAGGAGAAGTATACAGACACACTGGGCTCCATCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000034116-'2-17,'2-8,10-17=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.139 A=0.324 C2=0.031
Domain overlap (PFAM):

C1:
NO
A:
NO
C2:
PF0062115=RhoGEF=PU(11.4=62.5)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
ALTERNATIVE
(Vav)
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTTCCCAACAGAGGACAG
R:
CTGGATGGAGCCCAGTGTGTC
Band lengths:
162-271
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types