HsaEX6092941 @ hg19
Exon Skipping
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10828755-10883304:+
Coord C1 exon
chr19:10828755-10829079
Coord A exon
chr19:10870414-10870487
Coord C2 exon
chr19:10883155-10883304
Length
74 bp
Sequences
Splice sites
3' ss Seq
TCCCTCTCCCCCCCTCACAGGGA
3' ss Score
11.21
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
Exon sequences
Seq C1 exon
GAGAACCGGATGAGGCGGCGACCGTGAGGCCGAGCCGGGAGCGGGCGTCTTGCCGAGGCCCGGGCGGGCGGGGAGCAACGGCTACAGACGCCGCGGGGCCAGGTCGTTGAGGGTCGGCGGCGGGCGAGGAGCGCAGGGCGCTCGGGCCGGGGGCCGCCGGCGCCATGGGCAACCGCGGGATGGAAGAGCTGATCCCGCTGGTCAACAAACTGCAGGACGCCTTCAGCTCCATCGGCCAGAGCTGCCACCTGGACCTGCCGCAGATCGCTGTAGTGGGCGGCCAGAGCGCCGGCAAGAGCTCGGTGCTGGAGAACTTCGTGGGCCG
Seq A exon
GGACTTCCTTCCCCGCGGTTCAGGAATCGTCACCCGGCGGCCTCTCATTCTGCAGCTCATCTTCTCAAAAACAG
Seq C2 exon
AACATGCCGAGTTTTTGCACTGCAAGTCCAAAAAGTTTACAGACTTTGATGAAGTCCGGCAGGAGATTGAAGCAGAGACCGACAGGGTCACGGGGACCAACAAAGGCATCTCCCCAGTGCCCATCAACCTTCGAGTCTACTCGCCACACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.019 A=0.032 C2=0.173
Domain overlap (PFAM):
C1:
PF0035018=Dynamin_N=PU(11.5=37.0)
A:
PF0035018=Dynamin_N=FE(14.4=100)
C2:
PF0035018=Dynamin_N=FE(28.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGAAGAGCTGATCCCGCT
R:
GCAGTGCAAAAACTCGGCATG
Band lengths:
170-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)