HsaINT0050673 @ hg19
Intron Retention
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10916592-10919256:+
Coord C1 exon
chr19:10916592-10916643
Coord A exon
chr19:10916644-10919244
Coord C2 exon
chr19:10919245-10919256
Length
2601 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGCA
5' ss Score
6.37
3' ss Seq
CTAACTTTGCATATTCAAAGGGG
3' ss Score
3.62
Exon sequences
Seq C1 exon
TGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAG
Seq A exon
GTAGCACACCCCTCTGCAGTCTCCCGCTCTACCCTGGGGGCGGGAGGACGCTAAGTGACAGCTAAGCCCCCGTGATGGAGCTCGGCCTGTGTAAAGCCCCACCCCACAGCCTCAGTACCAGGCCATCTGCTCTCTCTAGAGGCCACTTAGGAATTGATAATTCTGGGAGATGGCCTGAGAGCCAACACTCTGGCAGGGCCTAGTGGGCACATTTTACCCACCCAGAAGGCCCTATGTGCCATCCAAGGCCAGGGTTAGAACTTGACTCTTGGCTGGGCACAGTAGCTCACACCTGTAATCCCAGCATTTTGGGAGGCCGAGGTGGGAGGATCACTTGAGGCTAAGAGTTTGAGACCAGCCTGGGCAACATAGAAAGACTCTGTCTCTACAAATAATAATATTTAAAAATTACCTGGGAGTGGTGGGCTCATGCCTATCACCCCAGCTACTTAGGAGGCCAAGGTGGGAGGGTCACTTGAGCCCAGCAGTTCATGACCATCCGGGGCAATACAATGAGACCTCATCTTAAAAATTAATAATAGGCTGGGCACGATAGCTCACACCTGTAATTCTAGCATGTTAGGAGGCTGAGGCGGGCGGATTGCCTGAGCTCAGGAGTTTGAGACCAGCCTGGCTAACATGGCAAAAACCCCATCTCTACTAAAAATACAAAAAATTAACCAGGCGTGGTGGCACGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGGATTGCTTGAACCTTGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCGCCACCGCACTCCAGTGTGGGTGACAGGGCCAGACTCTGTCTCCAAAAATAATAATAATAAAGATATAAATAAGAATTTTTCCCTTGAGCGGGGGTCTGTGACCTCTTTGAGCTTTCCAACACAGCCCCAGGGATTGGGAGCCCCTAGGTGAGAGCCGCTGGAAACTACATTGTCACTAGCAGCTCAGGGGAGCTTGGGATAGTTGAAGCCCCACACCTGGAGAAGCCCTGAGCCACAAAGGGTTGTACCTTGACATCTTAACCCAGCTAGAGGCCTTGTGAAATATGAACGGCTGTATCAATGCCTGCCTTCAGTACCTTATTATTATTATTATTATTTTGACACAGAGTCTCGCATTGTCACCTGGGCTGCAGTGCAGTGGCGCAATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGGTTCAGCCTCCTCAGTAGCTGGGATTACAGGTGCTCACCACAACACCAGGCTAATTTTTTTTTATTTTTTTCTTGAGATGGAGCCTTGCTCTGTGTCCCAGCTGGAGTGCAGTGGCACGATTTCAGCTCACTGCAACCTCCACCTCCCGGGTTCAAGCAATTCTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCCGCCAGCACGCCCAGCTAATTTTTTTGTATTTTTAGTAGAGAGGGGGTTTCACCATCTTGGCCAGGCTGGTCTCAAACTCCTGACCTGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGAATTACAAGCGTGAGCCATCACGTCCAGCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGCCACCAAGGCTGGAGTGCAGTGGCGCGGTCTCAGCTCACCACAACCTCCGCCTCCTAGCTTCGTGTGATTCTCCTGCCTCAGCCTTCTGAGTAGCGACGATTACAGGAGCCTGCCACCACCCCTGACTAATTTCTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCCCAGGTGATCCACCCGCCTCGCCCGGACAAAGTGCTGGGATTATCATGCCAGCCTTTATCATTAATTTTTAAGAAAACCTGGACGGGCACGGTGGCTCACACCTGTAGTCCTAGCACTTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAAGAGTTAGAGAACAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTAGCCTGGCATGATGGTGGGTGCCTATAATTCCACCTACTCGGGAGGTTGAGACAGGAGAATCACTTGAACCCAGGAGATGGTGGTTGTGGTGAGCCAGGATCACACCACTGCACTCTGGCCTGGGCGGCTGAGCGAGACTCCATATCAGGAAAAAAAAAAAGAAAGAAAGAAAAGGAAACCATAATCTTCGCAAAATTTCTGCCTATGTCCCTCCCTTCTCCCCATTGGGCAGGGGTGGGGGCGGGGACTCCACCATGTACCTTGCACGATCATAGAGCCTACTGGAAGGAAGAACGTAACCATTGCATGATTTATTTTTGCGCTTGCCGTAGGTAATACATATGTTGTTGCTTTTTTGTTTCTTGAGATAATAATGAATTAAATATTAACACCATGAATATGATTAATAGCATGTAATTTTTTTTCTTTTGCTGTTTTTTCCCCTGCTCTTCTCTTCTCCTGTTTTTGTGCTTTTCCTGCTTTTTCTTTGTCCCCTTCACGTCCCTTCCATCTCTTTTCCTTTGCCTGCTCTTCCCTGATTTACCCACAACCCTAACTTTGCATATTCAAAG
Seq C2 exon
GGGGAGATCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-DNM2:NM_001190716:13
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=PD(10.1=66.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)