HsaINT0101782 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127454566-127455607:+
Coord C1 exon
chr5:127454566-127454610
Coord A exon
chr5:127454611-127455400
Coord C2 exon
chr5:127455401-127455607
Length
790 bp
Sequences
Splice sites
5' ss Seq
AAGGTATCA
5' ss Score
7.22
3' ss Seq
CTTCTCATTTCTCTTCACAGACC
3' ss Score
11.5
Exon sequences
Seq C1 exon
GTGCTTTTGGACTTGACAGAAGCTATATGGGAAAATCCTTAAAAG
Seq A exon
GTATCATGTAAATTTGAAGAAGAAATCAGAAGCACAATTAAATTTTTTTTAACCTCAAAGACTGAAATAGTTTTTAAACAAGCTAGAATGGCAAGAGAAAATGTAGAATTTTTAGTGTGGTCAGTTACTACAGCAAACACACAAACATGTGTGACTGACATCAAGAAAGTGACCAGAGGTGGTCCTTGGTAGAGCTTAAGTCTTTGGGGAACAAAAGATTCAGTTTGCTGAGGAAACACTCATATTTCATTTAAAAGAAATATGGCTTATGGGGAGACGGAAACATATAAAGGGAAATAGCCGGGACAATAAGAAAAGATCCACATGGTTACATGTTGACCAAGTTCTGCTGTTCAGGATGGGTGTGCATGATTAGATGCCTAGTACAGAGCTTTTACTAGGAGTCCTCCCAGCACAAATGCCTTCTTGTCATGATAATAGAGCCCTCTTGGTGCTCCTGGGGCCATCAACAGCTGGTTTCTTGATTGAACTTCTGTAAATTTTCTATTAATAAAACAAAACGTAATTGATTATATTCTAATGTGATCATAAAAATGAAATCAGTTAATGATATTGATGTCAGTACTCATCTTGGAGAGGAGCTAAAACTACTTTAGGGATGGGTCATTTTATAGCAGATTCTCTCCAAAACAAGTGGAAAAGGTACAGTATTATTTTCAGTGTGTAGAATTATGGAAACCTAGCTATAAAGAAAAACAGTAAAATATCACCAAGAAATGATGTTGCCAGTGACACAGCATTAGCTTTCTCTTCTCATTTCTCTTCACAG
Seq C2 exon
ACCTGGGAAAGAATTCTGAATATAATTCAAGTAACTGCTCCCTAAGCAGTTCTGAGAACCCATATGCCACTATTAAAGACCCACCTGTACTTATCCCGAAAAGCTCAGAGTGTGGTTATGTGGAGATGAAATCGCCGGCACGAAGAGATTCCCCATATGCAGAGATCAATAACTCAACTTCAGCCAACAGGAATGTCTATGAAGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.062 A=NA C2=0.514
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTTTGGACTTGACAGAAGCT
R:
TTCATAGACATTCCTGTTGGCTGA
Band lengths:
246-1036
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development