HsaINT0101804 @ hg19
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66191066-66198479:-
Coord C1 exon
chr15:66198423-66198479
Coord A exon
chr15:66191273-66198422
Coord C2 exon
chr15:66191066-66191272
Length
7150 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGAG
5' ss Score
6.38
3' ss Seq
AAATGTCTCTTGCCTTGCAGATT
3' ss Score
9.99
Exon sequences
Seq C1 exon
GTGCTTGTGGAATGGATAGACGTCAGAACACATACATTATGGACAAAGGCTTCAAAG
Seq A exon
GTAGAGTATCCAATCCTGCTGTCTTATTACAGAGGGCTTAGCAAGATAAAGAGTGCAGATCTGAAATGGCCAGGAATTCCACTTGAGACAAACTGTGTGTGCCTGCCCCCCACAGAAGGTTAAAAGACCACAGGGCCTGGGGCTGTTGGGTAGCTGTGCCCAGGAGGAGCAATCAATCATAATAATAATGAATTCATCTTTCGATTTCAGTTGCACCTGCTTAGCAAATGCTTGTGGGTTTTTTATAGATGCCAACTAAATGTCTTCGGAAATGTAAAGCGTCATTATCCAACCAATTAGTACGAGTTAAATTGATTATAAAATCTGAAATAAAGTTGATCTACCTGCCCCAGAGGCCTCCTGTCGTTGCACTAGCAAGGAATGCCACCCTGCACCTGCTGGCTTTCTGGGGGCACAAGGAATGAAAATGATACGCAGTGTTAATATTGTATGGCACTCCAACCTCAAGAGATCTCTGCCTCCAAGAGCAGAGAAGCCAAGACAAATCCCTAACACATGGGAACTGCAAGTTGGATCATCCCTCTAGGAAGTCTACAGGTGAAGCCAAAGATGAAAGGTCAGGTCCTGCCCTAGGTTTAAATGCCGGAATGTGTGAAATAGGGGGCTTTGGAACTCTGTCACTTGCCACTCTGTTGCTCATTAACTGTGACCTTAGACTGGACTGTGAGCTTTCCAAGGCTCAGTTTCCTCATCTGCAAGGTTGGGATAATTTTGCCTGTCCTATTGTCTAATGCCTGTCCTACTGTCTAACAAGGTTATCATGAGTAACCAATAAAATCACCAATGGGAAGTGTTTTTTGCATACTGTAAAGGTGGTACTAATGTAATGGGGCTATTCTTTTGTCTAGGAGGTCTATTTAAAACAGCTTAAGGCCGGGCACAGTGGCTCACACCTGTGATCTCAGCACTTTGAGAGGCCGAGGCAGGTGGATCACTTAAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAAACATACAAAAATTAGCCAGACATGGTGGCACACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACAAGAATTGCTTGAAGCCGGGAGGCAAAGGTTGCAGTGAACCCAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAACAAGACTCTGTCTCAGAAAAAAGCGCTTAAGCCAAACAGATATGACAGCAGAGGTCCCAATGCATATCCTAAATCTAACAGTGTACCAGAATCACCTGGAAAGCTTATTAAAAATACAGATATTCACACCCCATCTCCTCAAAACTCTGATGCAAATCTAGAGTGGGGCCCTGGAATCTGCATGTGTGAAGAGCACCCTCAGGGTACCCTTATGCAGCTTATTCCCCAAACACTGGTCTAGACTGACCCAGATGTCCCTGATTACCGTTCTAGTCTTTCAGACCTAGTTTTACATACACCAAGACACAACCATTCCCTAACCAAGAACAGCTAGTCGTCTACAGTCCTTTTGGGGAGATGATTAGATGTGGGGTGAGCTCAGGGTAGGGGATGGTGGTAAGTACTGCATTCTGAACAAGACAGCGATAAGGCTGAGTCACTATCGGCCTTTGTTAGGATATACACAGCCCAAGAGAACTGTCTGAGGACAAAAGGTCATCCCCAGCCAGCCAACAGACATTACTCCCTTGGAAGCATTATTTTGGCAATTTTCTGTGTGTTTTGACTTAAACCATCCAAATGAGGAACAGTAGGTAAGGCTGAAAACAAAGAACAGTTCTATTTCGTGACTATGACCTGGCACCTCAGTTTCTTTCTCAAAAAGGTATAAGGATTGGGCAGAAAGCTCTCTAAGGGCCTTTCTAGCTGAAGAACACGCATGACTCAAGCATGAATAAACTCAGGACCAGAAACCCCAATAACTGAACACACAACTTTCCTATGCACTGTGTTGTCCTGTACATTGATTAGGGTGGTTACTTTCAGATTCGCAATCATACATGTAAAACAAAGCTCAGGAAAGCAGTGTCTCTGCCTCAGCATACATTTCATTACTATTGTGTAGAATCATATATCTGACCTCTGAGTGCAGGCGAGGGCTCAGCAGGCAGCCAGCCAGATCTTATTTTACCACTCTGGCTACAATCATCCTTTAAAAAGAAAAGAGAGCTATGTAAGCAAATGTACCAGCAGGTGTTGGGGACCAATACATCAGAATAAGAGAACTGAAAAAGAGGAAAATATGATGTCACAGTTCAGAACTTTATAACAATACTTACCAAAACATGGAATAAATCCCACTAATTGGCTAACGCCCCCCGAAATAAACACTTAATAAGCTAGTCTAGCACAAATGAAACTAGTTCCTAAAACTACTGGGCCAAACCAAATCAGAACTACTAAGAATTAAGAGTCTCAGTGTTCTCTGAACTCAGTGGGAAAAAGCCCTAGCCTAGGAGTTAAGGAATGTGGGTTGTAGTCCTAGTTCTTGCTGTATGGTGCTGACCAGGTCACAGCACTGTTTTCTGGGTCTTGGTTTCTTCCACTATAAAACGATGGGGCTGTACTAACAGCATCTCTGAGGCCCTTTCAAGCTCTGACATTCCAAAAGCCTTAGTCAATGCCTGCCCTTTCCCCTGTTACTTACTGAAGAACTCCACTCACTGTCATCCCGGAGGTTAAGGGAGACCACTTACACTGCTCAACACCCTTCTATTTCCCCTTCTCCCCCTAGCACAGTGATTCTGCAACAAACTGCCTCGTGTTCAATTCCTTGTCAGCCATTTCAAATTGCTATTCTCCATCGCCTTTATGATGCTGGAATCCTTGAGCCCACTGTTGCTGCCACTTTCCCCACCTGTGTGCTCGTTCCCATCTAACTTCCAAGTCTGTCTTTGCGTAAACTTGGGCTCTTAGGTAGTTAGGAGCCCAATGACATCCTGAAGATTACTTTTTAAAGCCAGTGTTCTGACCCCAAGACCTCCTCCTCCTATCTCTCAATCAAGAGAAGGATGCTAATTTATGGCCCAGGAAGAGAAGAGGCAGTGTGGCCTTCTATTAATAGTAGCAAGCCAAGAAGCAAGAGATGGATATTCGGTGCCTGGGTTTTTCCCTGACAGTTAAGTTGGGCCTTAGTGGAGGTTAGCATGCACCTAGAAGCCAAGGTGGGCTCAGATCCCACACACAAGGTGGCCCTGGAAAGTCACTGCCTCTCTCTAGATTTGATGCTCCCTTTATAAAATGAAAATGTTTAGTTCATCTCAGAAGCCCCCTCTGTCTCTGACAGTGTATGACTATGTGGGGAGGCAGGAACCAGATGAGACCAAATGCCAGGGCATTACAGGACCAAGCCGCCAATCCTGATGCAAATGACAAGCCTTGGAGGAGTGACTCCCAGAGCTTGGGTAGCCTGGGTTGATGCTTCCTCTTTCTTTGCAAAATGCCCTGAAGGGCTGGGACTGGGACAGGGGTGGGGCTATGAAAGGATGAGGAAGTATCTAAGAGCAGCTGGTTATTCTTCCACTCAACCCTGCCCTCCCCTCTTGCAGGCAGGTGGATGACTCAGCTGGAGAACAAAGTGGCTTCCTGAGGTGGAGTTTCCAGCTTGCCCAGCCCTTCCCCATTCTCCAGTCCCAGTAGAGATGGGGTACAGAAGAGTCCATAATTCAACACCCTTTTCTCACCACCCAGCCAACACATACATGCACTGCTCCATCCTCTGCTCCTGTATGGAAGATACTTCCCCCTGAGCTTAGCCCCTCCCCACAGACATCAACTTCTCTTTTATCCATTTAGGATCATCCCCTGCTCCAGAGCCAACAATTGATTCCCCAAAACTTTAAAGTAGCCCCGACTTTTCTGGTGAAAATGAGAAGAGGCACTATCAACTGGCCGAGGTTCTTTTAGGCATTGAACTTCAAGGCTCTCCTACTGCCCTAACTCAGTCATGGGATATCCACAAAAAACTTAAGAGCTTAGCCTTTTTCTCTCAGCTGGGCTTAGCCCCATAGATGAAAGACATTCCTTGTTAAGGGTAAGGTGTAGCTGCTGCAGATACAGTTTGCCTTTAGAGATATGGACAGGAGCCCTGGATAACAAGACACGTAGTGAGGGAAAACATCTTGATTGGTATCAAGAGAAGACAGGGGTTGAGTCCTGACTAAACTATTTACTAACATTAGGAATTATATTAGCAAATTTTCTGAGCTTCAGATTCCTCATTCTAAAGTAGAAACAACAGTCCTTTCTGCCCAGCCCTATTCACGATGTAACAAGTTTCAAATGACCTAATTGGAATGAAGACTATACGTGCTACATAAAGTGGTTATTCCTCACATGTTAGAAAATATGCAGTTGAGGCAGCTGCAATAGCTTTTCTTTAAATACTACTAGTCCTCAGCTTCCAAACCAGAAGCTCTGTGCCTTACTGCCTTACTCCTTGACTGGTGAGTTCAGAGTAAGGTGGAGCTGCTGCAGATACAGTTTGCCTTTAGAGATAAGGACAGGAGCACTGGATAACAAGACACGTAGTGAGGGAAAACATCTTGATTGGTATCAACTAAGAGACAATAGGGGTTCAACTACTTACTAACATTAGGAATTATACTAGCAAATTTTCTGAGCTTCAGATTCCTCATTCTGAAGTAGTAATAGTCCTTTCTGCACAGCCCTATTCATTATGTAACAAGTTTCAAATGACCTAATTGGAATGAAGACTATAATTGCTACATAAAGTGGTTATTCATCACGTTAGAAAATATGCAGTTGAGGCAGGTGCAATAGCCTTTCTTTAAATACTACTAGTCCTCAGCTTCCAAACCAGAAGCTCTGTGCCTTATTGCCTTACTCCTTGGCTGGTGAGTTCAGAGAACCCAAAGTGGGACAGATGGGCCATGCTGGGGTTCTTGGACTTACCACCACTTCCTTGTACTAAAAAACTAAGTACCCTCTAAGGGGCAAATTTATGTGGTTTGGGCAGGTCACAGTCAAGGGTCCAAGCAGCTATGTAGAAATGAAGTCACCTGTGCACATGGGGTCTCCATACACAGATGTGCCATCCTTGTCGACATCTAATAAAAATATATATGAAGTTGGTAGGTGTCTCAAATAAGTAACTTAGTGAAATCAGGGCACTAGTGCAGCATTTGAAATAAAAGTCAACCAGCATCTGGGCCTATATCTGGCCTCCCTTTAGGCCTTGCTGGTGCTAGCTGAGATCGTTCAGTGTCTCGCAAGGATGTTTTCTCCTTCTCTCTAGAGTCATATGCTAAAGAGGCCACAATCTTAAGACGTGACTAAAGCCAATATCCCTCTCTACTTCTGGGCTAAATTGTGATGGAAAATGCTGAGCCTGGTTCTACAGAGTTTGCTCTGCTAGTGATAAGCAGTGTGATCCTGAGGAAGTCAATTTCCACTCTAAATCTCATAAGCAATGACTTCCTCAATAAGCAATGAGAGGAGAAGGAGAGAGAGAATTATTGCTCTACCTATACCACAGAGTGTTGTGTGAACACTTGAAGGAACTAATGGCTGAACATATTTTTGTACAAGATTGAGGAAATACTATCTGCTGAAACAAACATCAACAGAATGGACATCTACTTTAACAGAAAAGTAAATACTCTTCCAACCAGTTGCCTTTTATGGGAGATAAGACTACTTGTGGTGGCACACATCTAGCTACTTCAGCCATACGGAGTGTTCTGCTTTCAGGGTCCCAAGGTACATCTAAGACATCCATTGAGTTACATTATCACTTTCACTTTTTACCATTTTCATTACTCTCACAAATTGGAGACAGCATAAATAGCAGCCCAAAATGTAAACTGTGGTAGTTCTAGTGACAGATCATCCAAGAATTTCACCATCTGCTACCTTTCACAGAAATTTAGTGCTGAGACGCCTTTTAGATCACTTCTATCAACTCAAGCAGCTCAGTGCTTGTGTCTAGATCCCTTGTCTAGCAGAGCTTCACAGAAGAAGGTCAGAGCTGCTAGATTAGAGTTTACTGCTCTTTCCAGGCAAATCCTGCCTTGCCTGGGACTATCTGCAGGAGTCAGTGATCTTCCCCAAACAGAGAATGGTACAGAGGCTGAAAGAGGGAATCCCCTTTCCTTCCGTAACTCCCAGTCACTAAAGAACCCATCTTCCTCCAGTGAAACTACAGTACCTCATTTCATATTTGGAAACCAGCCTGCATCCTTTTGTACTCTGAAGTCTCGGGGATGGTACAACTATACAACTGAGAGGTGGCAGGAAAGGAAGCATGAGCTCTAGTATCAGAAAGATACTGCTGAAATAGGTTTCAGTTAGCATTGACAAGAACAGGGGGGTAAGCAACCCAAGAACACGTTACAGGCTTGCTAGAAAACAGGAACTTTCCAAAGGCTAGCTTAAGACTGACGTGCTTTTTACACCTCAATTACACTTCAGTCTACCCTATTCTGATGAGCTCCTGGAGGGCAGGGATACTGCTAAGAGTCTGCCACTTATAGGCTGTCAAATTGCTGACATCTGTGCTAAAACATGCATGCCTACTTCTTCTGAACCTAAGCTTCTCAGTCATTGAAAACAATTCAAGTCAGGTGTGGTGGCACGTACCGATAATACCAGCTACTCAGGAGGCTGAGGCGGGAGAATCACTTAAGCCCAGGAGTTTGAGACCAGCCTAGGCAACATCTCAAAAAAGAAGAATTCACAAGAATATCATCACAGAAAATGCACAGGCCAAGGAGTCCAAAGGCATGGATTCAATTCTTGGCACTGCCATTCACTAGCTGTGTGACTTTAGCTAAGTCACTTCATATCTCTGAGCCTTGATCTCATAAAATGCAACTATCAGCAACCCTTGCAGGAATTTACAAAAATTAAATACATGTCAAAGCATATTATGCATATCTTGAATTAATACCCAACTACTAAAAACAAAAATGTTCCTATCCTCCAAAAACATAAGTTTCTTTGGAAAAAGAACTCTGCCTACCTGGGAGAGCACTTCTCAGCACATTTAATAAGTAAATAAATCTTGGATTATCCTGGCTTTTCCAGCTCTAAGATCCTGAAGGCACATAAACTCAACTGCAGTCTGCTTCTGATATTAACATGAAGACTTGTATTCTTGCTTGTCCTAAGAAATGTCTCTTGCCTTGCAG
Seq C2 exon
ATTACATGAAAGAATCCGTGTGCAGTTCTAGTACTTGTTCCTTGAATAGCAGTGAAAACCCTTACGCCACAATTAAGGACCCACCCATCCTCACCTGCAAGCTTCCAGAAAGCAGCTATGTAGAAATGAAGTCGCCTGTGCACATGGGGTCTCCGTACACAGATGTGCCATCCTTGTCGACATCTAATAAAAATATATATGAAGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-MEGF11:NM_032445:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.050 A=NA C2=0.301
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)