HsaINT0107739 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10539052-10541252:-
Coord C1 exon
chr17:10541126-10541252
Coord A exon
chr17:10539171-10541125
Coord C2 exon
chr17:10539052-10539170
Length
1955 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGC
5' ss Score
8.69
3' ss Seq
CTATTTCCTTCTGGACACAGGTG
3' ss Score
7.93
Exon sequences
Seq C1 exon
GCAAATCTGGAAAAAATCTGCCGAACCCTGGAGGATCAGTTAAGTGAGGCCAGGGGCAAGAATGAGGAAATTCAGAGGAGCCTGAGCGAGCTGACCACACAGAAGTCTCGTTTGCAGACCGAGGCTG
Seq A exon
GTAAGCCACGTGCAGAAAACCCGTGGGGCCAAAACCTCCTGGCACCCAATGGGCGTAGCTGGCCAAAACCAAGGGCAGGGTGTGTTTGAGGGAGAATCTCTAGGGAAGCATCTTTTCAGGAGAGAAGAAATTGAAATAACTCATAGAAAGAGCCATTTGAAATAGCCTGAAGGGAGAGAACATTGAGAGTTCAGTAAGAATAAGAGAGAAAGAGGAGTAGACCAGAATGAGAAGGGGCTCAAAATATCATCTCATTCAAACTCTTTCAAAATTAATATAAACTTGCATCAGACAGACTCTGATGGGCAGAAATGAGACTAGAAACTAAGAGCCAGGGCCTTGATACTTCTTAACTCAGATATTCATTGTCTGCGTCCAAGTTTTTGAGACTAAAGAGAGAAACATGGCCAGTGTTTAAAGGTCCTGGTGTATAATAAAAACATAAGGGAGGCCGGGTGTGGTAGCTCATGCCTGTCAACCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCGACATGGTGAAACCCCGTCTCTATTAAAAATACAAAAATTAGCGAGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTATGCCATTGCACTCCAGCCTGGGCAACAAGAATGAAACTCTGTCTCAAAAAAAAAAAAAGTTTAAGGGAATGTTATTTGGAGTTTTCGCCTAGAAAATGTGGCTTCACCCAGCCCTGGTGCATCCTCACAGGTGAATCCATCCTCGGCTGGCAGTCACAGCCAAGACAATGAAGAAAAGAAGTTTGGTAGCCACATTTTTTTTTTTTTAGACAGAGTCTCACTCTCTGTCACCCAGGCTGGAGTGCAATTGTGTGATCTCGGCTCACTGCAAACTCCGCCTCCCGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGACGCATGCCAACACACACGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTGTGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCGCCTGCGTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTATGGTGGCCACTTTTACCATGTTGGGGGATTCACGTCTGGAGCCATAAAGCCCCATTCTATGTTTTTCTCTTACCTCTATGTAAGCATATAAACTTGAACTTACCCTATTCCCCCAAGAGTCTAACTAGAGATATAAAGCTCTAAGTATTTCCCTATGTATTTGTCGATAACAAATCAATAAACAGCTGGAAACACCTGCCACTGGGGAGGTCTGATGGGAGTTATTAGGTGCTCCTGGTAACGTTTACATTTACAGTTCTTCTCAATGGATTTTTTTTTTGACAGACATCAGTCCCACCTTCCAGTAGTTTACAACAATATCTTTTTTTTTTTTTTTTTTTTTGAGATTGAGGCATGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCCAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCCCATGACCACGCCCGGCTAATTTTTGTTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTTGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCTGGCCTACAACAATACCTTATCAGTTCTGCTTTCAGTTTCCTTTTCATGAACCATATACCTTCTCCCTGAAGAAGAAACCATATCTTATCATTTTCTGTCTCCCCAGATCTTAGCACAGTGCCCTACACATAATAGAAAGTTGGTGAGTGAATGAGTGAATAAATGAAATGAAACTATTTCCTTCTGGACACAG
Seq C2 exon
GTGAGCTGAGTCGTCAGCTGGAAGAAAAAGAAAGCATAGTATCCCAACTTTCCAGGAGCAAGCAAGCCTTTACCCAGCAAACAGAAGAGCTCAAGAGGCAGCTGGAGGAAGAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.628 A=NA C2=0.700
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.9=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAATCTGCCGAACCCTGGAG
R:
TTCTCTTCCTCCAGCTGCCTC
Band lengths:
230-2185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)