HsaINT0107739 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10635735-10637935:-
Coord C1 exon
chr17:10637809-10637935
Coord A exon
chr17:10635854-10637808
Coord C2 exon
chr17:10635735-10635853
Length
1955 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGC
5' ss Score
8.69
3' ss Seq
CTATTTCCTTCTGGACACAGGTG
3' ss Score
7.93
Exon sequences
Seq C1 exon
GCAAATCTGGAAAAAATCTGCCGAACCCTGGAGGATCAGTTAAGTGAGGCCAGGGGCAAGAATGAGGAAATTCAGAGGAGCCTGAGCGAGCTGACCACACAGAAGTCTCGTTTGCAGACCGAGGCTG
Seq A exon
GTAAGCCACGTGCAGAAAACCCGTGGGGCCAAAACCTCCTGGCACCCAATGGGCGTAGCTGGCCAAAACCAAGGGCAGGGTGTGTTTGAGGGAGAATCTCTAGGGAAGCATCTTTTCAGGAGAGAAGAAATTGAAATAACTCATAGAAAGAGCCATTTGAAATAGCCTGAAGGGAGAGAACATTGAGAGTTCAGTAAGAATAAGAGAGAAAGAGGAGTAGACCAGAATGAGAAGGGGCTCAAAATATCATCTCATTCAAACTCTTTCAAAATTAATATAAACTTGCATCAGACAGACTCTGATGGGCAGAAATGAGACTAGAAACTAAGAGCCAGGGCCTTGATACTTCTTAACTCAGATATTCATTGTCTGCGTCCAAGTTTTTGAGACTAAAGAGAGAAACATGGCCAGTGTTTAAAGGTCCTGGTGTATAATAAAAACATAAGGGAGGCCGGGTGTGGTAGCTCATGCCTGTCAACCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCGACATGGTGAAACCCCGTCTCTATTAAAAATACAAAAATTAGCGAGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTATGCCATTGCACTCCAGCCTGGGCAACAAGAATGAAACTCTGTCTCAAAAAAAAAAAAAGTTTAAGGGAATGTTATTTGGAGTTTTCGCCTAGAAAATGTGGCTTCACCCAGCCCTGGTGCATCCTCACAGGTGAATCCATCCTCGGCTGGCAGTCACAGCCAAGACAATGAAGAAAAGAAGTTTGGTAGCCACATTTTTTTTTTTTTAGACAGAGTCTCACTCTCTGTCACCCAGGCTGGAGTGCAATTGTGTGATCTCGGCTCACTGCAAACTCCGCCTCCCGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGACGCATGCCAACACACACGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTGTGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCGCCTGCGTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTATGGTGGCCACTTTTACCATGTTGGGGGATTCACGTCTGGAGCCATAAAGCCCCATTCTATGTTTTTCTCTTACCTCTATGTAAGCATATAAACTTGAACTTACCCTATTCCCCCAAGAGTCTAACTAGAGATATAAAGCTCTAAGTATTTCCCTATGTATTTGTCGATAACAAATCAATAAACAGCTGGAAACACCTGCCACTGGGGAGGTCTGATGGGAGTTATTAGGTGCTCCTGGTAACGTTTACATTTACAGTTCTTCTCAATGGATTTTTTTTTTGACAGACATCAGTCCCACCTTCCAGTAGTTTACAACAATATCTTTTTTTTTTTTTTTTTTTTTGAGATTGAGGCATGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCCAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCCCATGACCACGCCCGGCTAATTTTTGTTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTTGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCTGGCCTACAACAATACCTTATCAGTTCTGCTTTCAGTTTCCTTTTCATGAACCATATACCTTCTCCCTGAAGAAGAAACCATATCTTATCATTTTCTGTCTCCCCAGATCTTAGCACAGTGCCCTACACATAATAGAAAGTTGGTGAGTGAATGAGTGAATAAATGAAATGAAACTATTTCCTTCTGGACACAG
Seq C2 exon
GTGAGCTGAGTCGTCAGCTGGAAGAAAAAGAAAGCATAGTATCCCAACTTTCCAGGAGCAAGCAAGCCTTTACCCAGCAAACAGAAGAGCTCAAGAGGCAGCTGGAGGAAGAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.628 A=NA C2=0.700
Domain overlap (PFAM):
C1:
PF0003816=Filament=FE(15.2=100),PF0157614=Myosin_tail_1=FE(10.9=100),PF131661=AAA_13=FE(16.4=100),PF059116=DUF869=PU(40.2=90.7)
A:
NA
C2:
PF0003816=Filament=PD(1.4=10.0),PF0157614=Myosin_tail_1=FE(10.1=100),PF131661=AAA_13=FE(15.2=100),PF059116=DUF869=FE(40.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAATCTGCCGAACCCTGGAG
R:
TTCTCTTCCTCCAGCTGCCTC
Band lengths:
230-2185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development