HsaINT0108170 @ hg19
Intron Retention
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:7593]
Coordinates
chr5:16703034-16704794:-
Coord C1 exon
chr5:16704688-16704794
Coord A exon
chr5:16703268-16704687
Coord C2 exon
chr5:16703034-16703267
Length
1420 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
3' ss Seq
TTGTTTTCTTTCATTTTCAGAAA
3' ss Score
12.11
Exon sequences
Seq C1 exon
GTCTTTCTTCGAGAATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGCCATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGCACG
Seq A exon
GTAAGAACCCCACGCTGAGGGGATAAGGCAGGAAGCTCCATGAGGGGGTCCTTCCTTCCCAGTGTGTTCCAGTGGAGTGGCCTGAGGTTTTTGAATTGAGGGGAGCCTCAGGTCAGGCCTCCTAAGCAGCCACTCCCGAAACCTAGCTAGCCTGACTGGGCAGCAGGTAGGAAAGGGAGCTCTGCACTTTTTGACTTCTCAGGTAGAAAGAACAGTGACAGCAGGGAACTCTACTGAGATCTATTTATTTATTTGAGGCAGGGTCTTACTCTGTCTCTGAGGCTAGAGTGTGGTGGCACGATCATGGCTTATTGCAGCCTTGACCTCCTGGGCTCAAGCAATTCTCTCACCTCAGACTCCCAAGTAGTTGGGACTACAGACACACACCACCATGCCTGGCTAATTAAAAAAAAATTTTTTTTTTAGAGATGGGTCACTTCATGTTGCCCAGGAGGGTCTCAAACTCCTGGGCTCATGGGATCCTCCCGGCTGACAAAGTGCTGGGATTACAGGTGTGAGCCACCGTACCCAGCCTTCTCCTGATATTTAAATTATTTGCTTACTTCCTCTGCGTCAGGTCTTGAAGCCACAGCGGCCTGGCTGTTCACCTTGGTGTTATCATTTTGGCTATAGAGACCCATCCTCCAGCTGTTTGAGGAATGAGGTGACTTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCGCTCGTCTGGCTGGAGTGCAATGGTGCGATCTCAGCCCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGAGACTATAGGTGCATGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTTCGTGATCCATCCGCCTGCCTCGGCTTCCCAAAATTCTGGGATTACAGGCATGAGCCACCGCACCTGGCCTGAGGCAACTTCTCCTCATGTGCGTTTTAGTTGCATCCACTATGCCCGTGAAACACTACGTGTTACATTTTCTGAAGCACAAAGCTGTCCTGCTGTGATGATTTTTTTCATATGAACAGGAGAATATATCAGATCTCTTTGGGAACTATTTACCCAACTTTCTGCCAAGACTACTTAAAGCCAACATGAGGGGTTATGTGTTTATTTAGCCAAGATAGTGATAGGCTTCTTACTTTAGTTTTGTTTGTTATTATTTCTTTGTTTTTCTCCTGTTTTGTTTTGACCAAAGGGGCCTCCTTGTTCTCTCCAGTTTCCATAATGAGAGTCTCATTCTAAAACTGGGTCCTCTTTTGTCTTGTAGCCTTGATGTGAGCTCATTTGAATAGCTCAAAGCCTCATTACTTCAATGCCGATTCTCTTGTTTTCTTTCATTTTCAG
Seq C2 exon
AAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTACAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCTGAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAGAGTTTACAGACAATTGCTGGCAGAGAAAAGGGAGCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555-MYO10:NM_012334:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.229
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(3.6=8.3),PF0061222=IQ=PU(76.2=44.4)
A:
NA
C2:
PF0061222=IQ=PD(19.0=5.1),PF0061222=IQ=WD(100=25.3),PF0061222=IQ=WD(100=26.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTCGAGAATCCTTGGAACAGA
R:
TTCTTCTTCCTCCCGTTTCTTCT
Band lengths:
334-1754
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)