HsaINT0108170 @ hg38
Intron Retention
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:HGNC:7593]
Coordinates
chr5:16702925-16704685:-
Coord C1 exon
chr5:16704579-16704685
Coord A exon
chr5:16703159-16704578
Coord C2 exon
chr5:16702925-16703158
Length
1420 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
3' ss Seq
TTGTTTTCTTTCATTTTCAGAAA
3' ss Score
12.11
Exon sequences
Seq C1 exon
GTCTTTCTTCGAGAATCCTTGGAACAGAAACTGGAGAAGCGGAGGGAAGAGGAAGTGAGCCACGCGGCCATGGTGATTCGGGCCCATGTCTTGGGCTTCTTAGCACG
Seq A exon
GTAAGAACCCCACGCTGAGGGGATAAGGCAGGAAGCTCCATGAGGGGGTCCTTCCTTCCCAGTGTGTTCCAGTGGAGTGGCCTGAGGTTTTTGAATTGAGGGGAGCCTCAGGTCAGGCCTCCTAAGCAGCCACTCCCGAAACCTAGCTAGCCTGACTGGGCAGCAGGTAGGAAAGGGAGCTCTGCACTTTTTGACTTCTCAGGTAGAAAGAACAGTGACAGCAGGGAACTCTACTGAGATCTATTTATTTATTTGAGGCAGGGTCTTACTCTGTCTCTGAGGCTAGAGTGTGGTGGCACGATCATGGCTTATTGCAGCCTTGACCTCCTGGGCTCAAGCAATTCTCTCACCTCAGACTCCCAAGTAGTTGGGACTACAGACACACACCACCATGCCTGGCTAATTAAAAAAAAATTTTTTTTTTAGAGATGGGTCACTTCATGTTGCCCAGGAGGGTCTCAAACTCCTGGGCTCATGGGATCCTCCCGGCTGACAAAGTGCTGGGATTACAGGTGTGAGCCACCGTACCCAGCCTTCTCCTGATATTTAAATTATTTGCTTACTTCCTCTGCGTCAGGTCTTGAAGCCACAGCGGCCTGGCTGTTCACCTTGGTGTTATCATTTTGGCTATAGAGACCCATCCTCCAGCTGTTTGAGGAATGAGGTGACTTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCGCTCGTCTGGCTGGAGTGCAATGGTGCGATCTCAGCCCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGAGACTATAGGTGCATGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTTCGTGATCCATCCGCCTGCCTCGGCTTCCCAAAATTCTGGGATTACAGGCATGAGCCACCGCACCTGGCCTGAGGCAACTTCTCCTCATGTGCGTTTTAGTTGCATCCACTATGCCCGTGAAACACTACGTGTTACATTTTCTGAAGCACAAAGCTGTCCTGCTGTGATGATTTTTTTCATATGAACAGGAGAATATATCAGATCTCTTTGGGAACTATTTACCCAACTTTCTGCCAAGACTACTTAAAGCCAACATGAGGGGTTATGTGTTTATTTAGCCAAGATAGTGATAGGCTTCTTACTTTAGTTTTGTTTGTTATTATTTCTTTGTTTTTCTCCTGTTTTGTTTTGACCAAAGGGGCCTCCTTGTTCTCTCCAGTTTCCATAATGAGAGTCTCATTCTAAAACTGGGTCCTCTTTTGTCTTGTAGCCTTGATGTGAGCTCATTTGAATAGCTCAAAGCCTCATTACTTCAATGCCGATTCTCTTGTTTTCTTTCATTTTCAG
Seq C2 exon
AAAACAATACAGAAAGGTCCTTTATTGTGTGGTGATAATACAGAAGAATTACAGAGCATTCCTTCTGAGGAGGAGATTTTTGCACCTGAAAAAGGCAGCCATAGTTTTCCAGAAGCAACTCAGAGGTCAGATTGCTCGGAGAGTTTACAGACAATTGCTGGCAGAGAAAAGGGAGCAAGAAGAAAAGAAGAAACAGGAAGAGGAAGAAAAGAAGAAACGGGAGGAAGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555:ENST00000513610:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.231
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.5=8.3),PF0061222=IQ=PU(76.2=44.4)
A:
NA
C2:
PF0061222=IQ=WD(100=25.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTCGAGAATCCTTGGAACAGA
R:
TTCTTCTTCCTCCCGTTTCTTCT
Band lengths:
334-1754
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development