HsaINT0108977 @ hg38
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]
Coordinates
chr2:127630778-127631363:+
Coord C1 exon
chr2:127630778-127630908
Coord A exon
chr2:127630909-127631205
Coord C2 exon
chr2:127631206-127631363
Length
297 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCCC
5' ss Score
5.77
3' ss Seq
ACCAGCCTCTAACCTCACAGGGC
3' ss Score
7.42
Exon sequences
Seq C1 exon
AGCTTGCTTGCCATGTCACCAGAGAAGAGGAAGCTGGCGGCTCAGGAGGGGCAGTTCACAGAGCCACGTCCTGAGGAGCCACCCAAGGAAAAGCTGCACACCCTGGAGGAGTTCTCCTATGAGTTCTTCAG
Seq A exon
GTGCCCCCCAGCCCCGCTCCGCCTCATTGCACCCCCACCTCCCAGCCCCACCTCACCTCATTGCACCCCCTGCTCCCAGCCCCGCTCCACCTCATTGCACCCACTGAGAGCTGCAGAGAGGCCACGCCACCCATGTGGAGCCTGCCTGGCCTTCCCAGGCCAGGGGAGTCAGGAGGGGCTTGCGGCAGGGTGGGGTGCTCTGGCCCTCCCACAGCCACTCAGGGGTGTCAGAGGACAGAGAAGCGTGGGACAGAGAAGGCCACAGGGCAGGCCTCACACCAGCCTCTAACCTCACAG
Seq C2 exon
GGCTCCAGAGAAGGACATGGTGAGCATGGCCGTGCTGCCCCTGGCCCGTGCCCGTGGCCACCTGTGGGCCTATTCCTGCGAGCCGCTGCGACAGCCGCTGCTCAAGCGAGTCCACGCCAACGTCGACCTCTGGGACATCGCCTGCCAGATCTTTGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994:ENST00000409816:34
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.409 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGCTTGCCATGTCACCAGAG
R:
ACAAAGATCTGGCAGGCGATG
Band lengths:
284-581
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development