HsaINT0176838 @ hg19
Intron Retention
Gene
ENSG00000144357 | UBR3
Description
ubiquitin protein ligase E3 component n-recognin 3 (putative) [Source:HGNC Symbol;Acc:30467]
Coordinates
chr2:170751691-170753245:+
Coord C1 exon
chr2:170751691-170751821
Coord A exon
chr2:170751822-170753016
Coord C2 exon
chr2:170753017-170753245
Length
1195 bp
Sequences
Splice sites
5' ss Seq
AAGGTATCT
5' ss Score
7.56
3' ss Seq
TTCTATTAAAATGTTTACAGGTT
3' ss Score
6.4
Exon sequences
Seq C1 exon
ATCAATCCATAATGGATGTTTTGAAGCATAAAAGCTTCCTAGAAGAACTATTATTTTGGACTATAAAATATGAATTCCCTCAAAAGATGGTAACTTTCTTACTCAACATGCTTCCAGATCAAGAGTATAAG
Seq A exon
GTATCTATATATTTTCCTGCTTTTCTGAACTTAGCTTTTCTTTCTTTGCCTTTCATTATTAAATCTTTTTTTGATATATTTCTCAGGTGAAGGTTGATATAACACTATAAACAAGTGTTAGTTTCTTCTCTTGATAACACAAGTTCTTCACAAAAGGCACAGTGTCTTAGCTTTGTGGCAAAGCAGCATTACTCAGCAGAATTCCAAAGGATTGCTTTTCTGCATGGAACTTGGTCTGGAGGGAATGCTGGGGAACAAACATTGAAACCACAATTTTTATTTTGCAGAAATAAATATGTAGTTACAAATTGTTCTAAATCCTCTGAAGAAGAGTACAAGGTGCTATAAGAATGTTTAATGGGGGCAATTGAATTTAGATTGTGAGATCAGGCTGGGAAAAGCATGGGTTGAAAAGTTGCTGGTCACAACTGCTAAAGAGAGAACAGTTATTGACTCATATACAAATGTTGGCAGGTGAAGTTTCTAGTCCCAGGGGGTCAGAACCCACCTGTTACTATCTTACGGTTATGGCAAAATGACGAAGCTCGGTGTATGAAAAGAAAATAAAGCATGCTGTTATTTTTATGGTGTAGGTTAGGAGAGACACTTTGATAGTGTCATTGTTTTGTGTGTCTTTATATCTGCTAAAAAAAAAAACCAGAGAAAATGTACATGTAAAGGAAATAAGAGTAAAAATAAATACGGCTGGGCGTGGTAGCTCACGTCTGTAGTCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACCAGAGGTCGGGAGTTTGAGATCAGTCTGGCCAAACCCCATCTCTACTGAAAATACAAAAATTAGTTGGGCGTGATGGCGTGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCAGGCTTGGGGACAGAGCAAGACTCCGTTTTGGGGGAAAAAAATTTTTTTTTTTTCTTTAACCATCAAAATATTTTGCAAATGTTCCAAAAAAGTGAAAGACTACCTCACCATCGAGATTTTTTTTAAGTTATCTTGGGCATTATTATAAATTAGTAATAGCTGTAAAATGTTAACATGATATATTGAAAATGATTTTAAATTAAAAATTAAAACTAATGTGTTTTTTCCTTTCTATTAAAATGTTTACAG
Seq C2 exon
GTTGCTTTTACAAAAACTTTTGTTCAGCATTATGCTTTCATTATGAAAACACTGAAGAAAAGTCATGAATCAGACACAATGTCTAACAGAATTGTGCATATTAGTGTTCAGTTGTTCAGCAATGAGGAGCTAGCCAGACAGGTAACAGAAGAATGTCAGCTGCTGGATATTATGGTCACTGTGCTATTATACATGATGGAAAGTTGCCTTATTAAAAGTGAGCTACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144357-UBR3:NM_172070:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0065015=CRAL_TRIO=PU(63.1=84.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATAATGGATGTTTTGAAGCAT
R:
TGTAGCTCACTTTTAATAAGGCAAC
Band lengths:
353-1548
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)