HsaINT0177861 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73051189-73052311:+
Coord C1 exon
chr10:73051189-73051578
Coord A exon
chr10:73051579-73052223
Coord C2 exon
chr10:73052224-73052311
Length
645 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
TGACTTCCCTCTCCCCCTAGGGG
3' ss Score
13.4
Exon sequences
Seq C1 exon
GCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCCGGCATCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACCAACTCTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACCACGGGCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGCACATACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCTCGGTTCCCAGCAGCTCTTGGGCCTGCCCCGAGACCCAGGGAGCAGCGTCAGCGGCACCTTTGGCTGCCTGGGTGGGAGGCTCAGCATCCCCGGCACAG
Seq A exon
GTGAGCCCCTGCCCTGCTTGTGCGTCAGCCTGGCCTTAGCACCTCCTCTGTGGACTGCCCCAACACCCATCCAGCAGAAGATAGGGCTGCCCTAATCCCATCTCACAGATGGGGAAAGGGAGGCCTGAAGGCAGGAAGTGAGTATAAAATAGAGAGGTCTGACTAGAAAAGCTAGGCTTCAAGCCTGCCTATGCCCTCACTAGGGCAGAGGAACCTTGGGCCAGCCATCTTCTAAGCTTCAGTGTCTCTGTTGTGTGAGAGAGAATATTCCAACGTAGTTCAGCAGACCTACAAAGCACTGTCCTGGAACTAGCAGCAGAGGGACAGGGGCGCCTGTTTTAGTTTGCAAAGCCAGCAATTAACAGCTTCCCAGCATCATATACTAAGCTAGGAGTAGAGCTGGCACTTGGACCTCCAGACACCATAGCAATGTCAGAGACCCCTGTCTTCCTAGACAAGCCAGCACTGGTCAGTGGCCTGGCCTCTGCTTGCATCCAGTCCCCAGACCCTGTCTCCCACCCCTGGCTGGGGACTACCTGGAGCTCAGGAGATATCTTTCTCTCCCAGCCCCAAGCTGGGGCCAACTTCCCAAACACTTGTTCTCCTAAGCTCCTGGACTCCCTGCTGACTTCCCTCTCCCCCTAG
Seq C2 exon
GGGTCAGCTTGCTGGTGCCCAATGGAGCCATTCCCCAGGGCAAGTTCTACGAGATGTATCTACTCATCAACAAGGCAGAAAGTACCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.126 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(20.4=16.0)
A:
NA
C2:
PF0079115=ZU5=FE(28.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACTCCACCGACAAAATCCCC
R:
TCTCGTAGAACTTGCCCTGGG
Band lengths:
358-1003
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)