HsaINT0186261 @ hg19
Intron Retention
Gene
ENSG00000163848 | ZNF148
Description
zinc finger protein 148 [Source:HGNC Symbol;Acc:12933]
Coordinates
chr3:124996570-124998091:-
Coord C1 exon
chr3:124997968-124998091
Coord A exon
chr3:124996654-124997967
Coord C2 exon
chr3:124996570-124996653
Length
1314 bp
Sequences
Splice sites
5' ss Seq
CAGGTATTT
5' ss Score
7.51
3' ss Seq
GGATGTGAAATTATTTTAAGGTG
3' ss Score
4.42
Exon sequences
Seq C1 exon
ATCCTTACAATAAATGAGGATGGATCACTTGGTTTGAAAACCCCTAAATCTCACGTTTGTGAGCACTGCAATGCTGCCTTTAGAACGAACTATCACTTACAGAGACATGTCTTCATTCATACAG
Seq A exon
GTATTTCTTGAATTAAAATGGGCTTGTGGCCATTAAAGTTATTATCTTTGTTATTTTCATCTTCGTGTAACTGTCATTCATTCCTAAGACCATAGCTAATCTGGCATTCCAAATCAGAGATTTTGTAGGCCAGAATGTCAGAAGGAAACCAGGAAAAACTCTTAAGTGAGAAAACAATTAGCATGGATGTGTAAAATTAATTAAATAGTCTTAATTGGACACCTGTTTGGCTTAATGTGCTCCATTTAGCTAGAGAAATGATTAAAGAATGTATTATTAAAAGCCTGTTTATCAGTGTTCATTTTTTGTGTGTGCAAAATGTCCAGGCAGAGTTTAAAACATGGATTTGGAAATCAAATATAAATAAATGATAGCTAAGATAATGAAATTGTAGAGAACAGTATTAAAGATGACAGACCTTTGGGTAAACAAACTAGACATGTAAGATGAAATGAGGAAGAAAAACAGTTATAAGGGAGATTCATTGAACTAGGAAAATAGTGTCCCAGAAGCTAGTAGAAGATAGAATTCCAAGCAGGATGTGACCAACAGTGCCAGTGCCCTAGGAGGATAGAGGTTAGAGAACCAAGAAAAAATCTTTGGAATAAATAGCAAGGAGATCACAAGTAGCTTTTCAGAAAGCAGAGTATAAGGGTTAAACCGCAAGTGGGCAGTGAAGAATTTGACTTAGAGTAGACTACTCTTTTAAGGAGGTGTAGTGAAAGAGAAGGAGAGAAAGTACTAAGGTAGAAGTGTTTCAGGACTGAAACAAGGTTTCTCAGCATAGAGCAGGCCAGAGAATACTTTCCTTAAAAGGAAAAGCCCCAGCAGAGAGAGAAAGTTTGAAGAGACAGGATCTTTTAAAAAAGGGATGTTTAGAAAGTTCTGAAGGTTCTGAAGAAAATATGTAAAAGGGCATAAATGGATGGTTAACTAGGGAGAAAACAGGATGGGCGCACCTTCTTCCAGATAAAAAGGAAGAAAAGATGTTTAGGACACGTGAGAACCTGTATTTCTTTCTCACCCCATGATGTTAAAATTCAATTTTAAATTGTTTTATTTATTTCCTTCCCCCCCTTGAATATATAGATCAAATTTAATCTTATTTTTCTGTGATTGTGAGAATATGAATTTTTAAATCCTGGGAAAAAAATTGAGAGGACATAAAATTCTGTTAATAACATTAAAAATTTGTATGGCTATTTTGTAATTTTCCAAAATTTGGGCATCTAAGATTTTTCTTTCCTCAGAAACAGTAACTAAAAACCGTTGTTTTATTCAGTAACTAATTTGTGGATGTGAAATTATTTTAAG
Seq C2 exon
GTGAAAAACCATTTCAATGTAGTCAATGTGACATGCGTTTCATACAGAAGTACCTGCTTCAGAGACATGAGAAGATTCATACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000163848-ZNF148:NM_021964:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.190 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127602=Zn_Tnp_IS1595=PU(70.5=73.8),PF134651=zf-H2C2_2=PU(38.5=23.8)
A:
NA
C2:
PF127602=Zn_Tnp_IS1595=PD(27.3=41.4),PF134651=zf-H2C2_2=PD(57.7=51.7),PF134651=zf-H2C2_2=PU(38.5=34.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTTACAATAAATGAGGATGGATCA
R:
CAGTATGAATCTTCTCATGTCTCTGA
Band lengths:
207-1521
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)