HsaINT1007176 @ hg38
Intron Retention
Gene
ENSG00000215704 | CELA2B
Description
chymotrypsin like elastase family member 2B [Source:HGNC Symbol;Acc:HGNC:29995]
Coordinates
chr1:15485901-15487437:+
Coord C1 exon
chr1:15485901-15486046
Coord A exon
chr1:15486047-15487284
Coord C2 exon
chr1:15487285-15487437
Length
1238 bp
Sequences
Splice sites
5' ss Seq
AACGTGAGT
5' ss Score
9.54
3' ss Seq
ATAACTCTGGCCTTCCTCAGGGA
3' ss Score
7.84
Exon sequences
Seq C1 exon
CCAACGGGGCTCTCCCTGATGACCTGAAGCAGGGCCAGTTGCTGGTTGTGGACTATGCCACCTGCTCCAGCTCTGGCTGGTGGGGCAGCACCGTGAAGACGAATATGATCTGTGCTGGGGGTGATGGCGTGATATGCACCTGCAAC
Seq A exon
GTGAGTACCAAAAATCAGGGGCCCCGCTCCATGACAAAATGTGGCTGGGGATGGGAAGAGGCTATGGAAAACCATCCCTCCATAGGTCCATCCTCCGACCTCCTGGCAGAAGCACCCGGAAATGGTACCAGATATATCAGAACCTGACCTTTGGCCAGGCATAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATGCCTTGAGGTCAGCAGTTCGAGACCAGCCTGGCCAACATGGTGAAATCCTGTCTCTACTAAAAATAAAAATTAGCCAGGCATGGTGGTGGGTGCCTGTAGTCACAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGAAGGCGGAGGTTGCAGTGAGCTGAGATGATGCCACTGCACTCCAGCCTGGGTGACAGAGTGAAACTCAAAAAAAAACCTGACCTTGTTCTTGTTTGTTCTTGTTTTGAGATGTTTTGAGATTCTCCTTGTAGTGTCCACCCATCTCACTGCTGGGAAGTCCTTCCCTGGGTCTCATCAAGGTCTCTCGTGACTGTCCTTCTGTATCCTTTCCTCTACGCTGGAAGGGAACCAAAGGAAAGTATTCCCTGGCTTAAGGCCTTTCTAAGATGACTTCTGGTTTTTCTGTTGAATTACTCTCATCAATGGCGCAGTGTGTCCCCTCCAGGTAGCTGTCACGGAAACCTTCCTGGAGACAGTGTCTTAACCACCAGGAATTGCTCTGTGTTGGACTTAGCAGTGAAGTGGGGATGGAGTAGGAAGGAGATCCACACGCCCTTCAGATCACACTGTGCCCTACACACTCTGCCCACATAGACCACCTGCGGGAAGACAGAACCAGTGGGGAAGAGCCTGGCAGCTGAAGTCTGGGATGTGGCCTCAGCTCCTTTACAAACTGCCTGTGCAACCTTGGGCAAGTCCCAACCTCTCAACACTCCAGTTTCTCCTCTTCCGTGGCCTGGGGATACTACGAATATTTACCTCATAGGATTTTGTGAGGATTAATGAGATGAGGCATAGAACATGCTTAGCTCAGCTCTAAGGAAGAATAAGTGTTGGCTCTTGTTGGAATTATGGTACCACCTTGAGCTATGACCACAAGGACCAGCTTCAGAGGACAGTGACCTGCAGCAGAACAATAGAAATGCATTGAGAACAATGGTTCCAATGGGCAGCCCCTTCCTCCCACTTCAACTCCCTATAACTCTGGCCTTCCTCAG
Seq C2 exon
GGAGACTCCGGTGGGCCGCTGAACTGTCAGGCATCTGACGGCCGGTGGGAGGTGCATGGCATCGGCAGCCTCACGTCGGTCCTTGGTTGCAACTACTACTACAAGCCCTCCATCTTCACGCGGGTCTCCAACTACAACGACTGGATCAATTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000215704:ENST00000375910:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(20.5=100)
A:
NA
C2:
PF0008921=Trypsin=PD(20.5=94.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTCTCCCTGATGACCTGAA
R:
TGATCCAGTCGTTGTAGTTGGA
Band lengths:
287-1525
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains