Special

MmuEX0002985 @ mm9

Exon Skipping

Gene
ENSMUSG00000024130 | Abca3
Description
ATP-binding cassette, sub-family A (ABC1), member 3 [Source:MGI Symbol;Acc:MGI:1351617]
Coordinates
chr17:24542190-24547116:+
Coord C1 exon
chr17:24542190-24542384
Coord A exon
chr17:24545770-24545843
Coord C2 exon
chr17:24546809-24547116
Length
74 bp
Sequences
Splice sites
3' ss Seq
ACCTGCTCTCTTCTCTGCAGGCA
3' ss Score
12
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GTGTATGACCAGCGAGCACCGCTCCTTGCCGTGGACAGGATCTCCCTTGCGGTCCAGAAAGGGGAGTGCTTCGGCCTGTTGGGTTTCAATGGAGCTGGAAAAACCACAACATTCAAAATGCTGACTGGGGAGGAGACCATCACCTCAGGGGATGCCTTTGTTGGTGGTTACAGCATCAGTTCTGACATCGGGAAG
Seq A exon
GCAGCATCCTAGAAGATGAGCACCAAGACATGGTCCATTATCATCTGCCTGGCTGTGACCTCAGCTGGGCCAAG
Seq C2 exon
CTTCATGAAGGGAAGATACTGGCTATGACTAGGTGCTGAGACCATTGGCTCCCAATGCAACTGCACAGGCATCCTTGGATGTCAATGTTCCTTCCAGTATGGACAGTGGACCGGGCTGATCTGATCCTGAGCCAGATGTCATCCCACAGAGCATCGGCAGCACAAGAGAGAGCTGTGGCCAGACTTGAAGCACATCCTCTGTTCCTAGCTCTGTGCCTTCAAGAAGTCACTGGCCACAGGATTGTCAGGGACCACTACAGGGCTGAGTAGTGTCATCTCTTGAGGATACACTTAAACATATTGTGATT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024130_MULTIEX3-4/5=C1-5
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref, Alt. Stop)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=NA
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0000522=ABC_tran=PU(37.2=83.1)

							
A:
NO

							
C2:
PF0000522=ABC_tran=PD(13.8=69.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000045285f1480A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000045285f5736A





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000045285, ENSMUSP00000078544, ENSMUSP00000113538
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr16:2277597-2277670 
HIGH PSI
HsaEX6041870
(ABCA3)
Human
(hg19)
chr16:2327598-2327671 
HIGH PSI
HsaEX6041870
(ABCA3)
Rat
(rn6)
chr10:13779120-13779193 
HIGH PSI
RnoEX6046385
(Abca3)
Cow
(bosTau6)
chr25:1797745-1797818 
Chicken
(galGal4)
chr14:13569818-13569891 
HIGH PSI
GgaEX6013161
(ABCA3)
Chicken
(galGal3)
chr14:14335201-14335274 
HIGH PSI
GgaEX6013161
(E1BVQ5_CHICK)
Zebrafish
(danRer10)
chr3:12541536-12541609 
HIGH PSI
DreEX6015414
(abca3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGACCATCACCTCAGGGGATG

				
R: 
CGGTCCACTGTCCATACTGGA

				
Band lengths: 
175-249

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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