Special

MmuEX0010870 @ mm9

Exon Skipping

Gene
ENSMUSG00000057110 | Cep110
Description
centrosomal protein 110 [Source:MGI Symbol;Acc:MGI:1889576]
Coordinates
chr2:34990988-34996141:+
Coord C1 exon
chr2:34990988-34991208
Coord A exon
chr2:34993152-34993328
Coord C2 exon
chr2:34996007-34996141
Length
177 bp
Sequences
Splice sites
3' ss Seq
AACATGCTGAATCTTTGCAGGAG
3' ss Score
6.04
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
GCCAGATAGCAGCAAACGAAGCTCTGAAGAAGGATTTAGAAGGTGTCATCAGTGGGTTGCAAGAGTACCTTGGAACCATCAAAGGCCAGGCAACTCAGGCCCAGAATGAGTGCAGGAAGCTACAGGATGAGAAAGAGACATTGCTGCAGAGACTGACAGAAGTCCAGCAGGAGAAGGAGGAACTTGAACTCATTGCCATGGATGCAGAAAATATGAGGAAG
Seq A exon
GAGCTTGCAGAGCTAGAAAGTGCCCTCCAGGAACAGCATGAGGTGAATGCATCCCTACAGCAAGCCCAGGGAGATCTCAGCGCCTATGAAACTGAGCTAGAGACTCAGTTAAAACTAAAAGACGCTGAAACCAGCCAGCTCAAGCAAGAGTTGGAAAAACTCCTAAGGCGTACTCAG
Seq C2 exon
TTAGAGCAATCGGTGCTTCAAACAGAACTGGAGAAGGAGAGAGAATCCCTCAGGGATGCCCTGGGCAAAGCCCAGTCCTCAGAAGAGAAACAACAGGAGAACAACGAGCTCCGTACACAGCTGAAGCAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057110-'19-21,'19-19,21-21
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.334 A=0.635 C2=0.804
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF059116=DUF869=PD(25.4=23.0),PF138511=GAS=PD(57.8=85.1)

							
A:
NO

							
C2:
PF0383610=RasGAP_C=PU(30.8=53.3)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000028237





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000028237f5031A, ENSMUSP00000108656, ENSMUSP00000108657, ENSMUSP00000108660, ENSMUSP00000118731, ENSMUSP00000119760
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:121135806-121135982 
ALTERNATIVE
HsaEX0014669
(CNTRL)
Human
(hg19)
chr9:123898084-123898260 
ALTERNATIVE
HsaEX0014669
(CEP110)
Rat
(rn6)
chr3:14331050-14331226 
HIGH PSI
RnoEX6016588
(Cntrl)
Cow
(bosTau6)
chr8:112452404-112452580 
HIGH PSI
BtaEX6036313
(CNTRL)
Chicken
(galGal4)
chr17:8357387-8357563 
ALTERNATIVE
GgaEX0026788
(CNTRL)
Chicken
(galGal3)
chr17:9061126-9061302 
ALTERNATIVE
GgaEX0026788
([1])
Zebrafish
(danRer10)
chr5:62741960-62742136 
HIGH PSI
DreEX6014115
(CNTRL)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGAGTGCAGGAAGCTACAGGA

				
R: 
CTGCTTCAGCTGTGTACGGAG

				
Band lengths: 
244-421

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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