Special

MmuEX0014228 @ mm10

Exon Skipping

Gene
Description
DENN/MADD domain containing 1B [Source:MGI Symbol;Acc:MGI:2447812]
Coordinates
chr1:139081173-139102093:+
Coord C1 exon
chr1:139081173-139081273
Coord A exon
chr1:139085883-139085928
Coord C2 exon
chr1:139101968-139102093
Length
46 bp
Sequences
Splice sites
3' ss Seq
CATATATATTTTTAATTTAGTGC
3' ss Score
5.67
5' ss Seq
GAGGTGAGT
5' ss Score
10.03
Exon sequences
Seq C1 exon
TTAACTGCCTGTCTCCATGGATCGGCTGCGCTACTCTACCCGATGTACTGGCAACACATATATATCCCCGTGCTTCCTCCACACCTGCTGGACTACTGCTG
Seq A exon
TGCCCCAATGCCATACCTGATTGGAATACACTCCAGTCTCATAGAG
Seq C2 exon
GTCTCGGCCTTGAAAAATAAGCTGAAGAAGCAGTCCACAGCTACGGGAGATGGAGTGGCTCGGGCCTTTCTGAGGGCTCAGGCGGCTTTGTTTGGCTCCTACCGAGATGCTCTGAGATACAAGCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000056268_MULTIEX1-12/15=11-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0214116=DENN=FE(18.2=100)
A:
PF0214116=DENN=FE(8.3=100)
C2:
PF0345514=dDENN=PU(40.3=64.3)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Other assemblies
Conservation
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCACACCTGCTGGACTACT
R:
GCATCTCGGTAGGAGCCAAAC
Band lengths:
135-181
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types