Special

MmuEX0038782 @ mm9

Exon Skipping

Gene
Description
Rap guanine nucleotide exchange factor (GEF) 3 [Source:MGI Symbol;Acc:MGI:2441741]
Coordinates
chr15:97588448-97589419:-
Coord C1 exon
chr15:97589273-97589419
Coord A exon
chr15:97588822-97588934
Coord C2 exon
chr15:97588448-97588536
Length
113 bp
Sequences
Splice sites
3' ss Seq
GAATGTGGCTCCTTCTCCAGGAT
3' ss Score
7.56
5' ss Seq
CCGGTAACA
5' ss Score
5.92
Exon sequences
Seq C1 exon
GGGCTGGTGACCACGTTGCACGAGGGAGATGACTTTGGACAGCTGGCTCTGGTGAACGACGCACCTCGGGCAGCCACCATCATCCTTCGAGAAAATAACTGTCACTTTCTGCGTGTGGACAAGCAGGACTTCAACCGCATCATCAAG
Seq A exon
GATGTGGAAGCAAAAACCATGAGACTGGAAGAACACGGCAAAGTGGTCTTAGTTCTGGAGAGAACCTCTCAGGGTGCTGGCCCTTCCCGTCCCCCGACCCCAGGCAGGAACCG
Seq C2 exon
GTATACGGTCATGTCTGGCACCCCAGAGAAAATCCTAGAACTGCTGTTGGAGGCTATGAGACCGGATTCCAGTGCTCATGACCCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022469_MULTIEX1-10/18=9-11
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.579 C2=0.290
Domain overlap (PFAM):

C1:
PF0002724=cNMP_binding=FE(56.5=100)
A:
PF0002724=cNMP_binding=PD(2.4=5.3)
C2:
PF0061815=RasGEF_N=PU(24.8=90.3)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCTGGTGACCACGTTG
R:
CTGTTGGGTCATGAGCACTGG
Band lengths:
236-349
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types