Special

MmuEX6002844 @ mm10

Exon Skipping

Gene
Description
pyruvate dehydrogenase kinase, isoenzyme 4 [Source:MGI Symbol;Acc:MGI:1351481]
Coordinates
chr6:5491591-5492777:-
Coord C1 exon
chr6:5492706-5492777
Coord A exon
chr6:5491830-5492014
Coord C2 exon
chr6:5491591-5491677
Length
185 bp
Sequences
Splice sites
3' ss Seq
ACTATGAATGTCTGGCTTAGGTT
3' ss Score
6.04
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
GTATATCCAGAGCCTGATGGATTTGGTGGAGTTCCATGAGAAGAGCCCAGAAGACCAGAAAGCCCTGTCAGA
Seq A exon
GTTTGTAGACACGCTGGTCAAAGTTCGAAACAGACATCATAATGTGGTCCCTACAATGGCTCAAGGCATCCTGGAGTATAAAGACACCTGCACAGTGGACCCCGTTACCAATCAAAATCTTCAGTATTTTTTAGACCGGTTTTACATGAACCGCATTTCTACTCGGATGCTCATGAATCAGCACA
Seq C2 exon
TCCTCATATTCAGTGACTCAAAGACGGGAAACCCAAGCCACATTGGAAGTATCGACCCAAACTGTGATGTGGTAGCAGTAGTCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000019577-'9-3,'9-2,10-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.068 A=0.000 C2=0.017
Domain overlap (PFAM):

C1:
PF104364=BCDHK_Adom3=PU(18.0=94.7)
A:
PF104364=BCDHK_Adom3=FE(37.8=100)
C2:
PF104364=BCDHK_Adom3=PD(11.6=63.3)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAGAGCCTGATGGATTTG
R:
CTTGGACTACTGCTACCACATCAC
Band lengths:
154-339
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types