MmuEX6101753 @ mm10
Exon Skipping
Gene
ENSMUSG00000064329 | Scn1a
Description
sodium channel, voltage-gated, type I, alpha [Source:MGI Symbol;Acc:MGI:98246]
Coordinates
chr2:66302366-66317946:-
Coord C1 exon
chr2:66317804-66317946
Coord A exon
chr2:66303592-66303712
Coord C2 exon
chr2:66302366-66302520
Length
121 bp
Sequences
Splice sites
3' ss Seq
TATGATCATTTTATGCCCAGAAA
3' ss Score
4.68
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
TCATTGATGAGAGTGATTATATGTCATTCATAAACAACCCCAGCCTCACTGTGACTGTGCCCATTGCTGTGGGAGAGTCTGACTTTGAGAACTTAAACACAGAAGACTTTAGCAGTGAATCAGATCTAGAAGAAAGCAAAGAG
Seq A exon
AAACTCAACGAAAGCAGTAGCTCCTCAGAGGGAAGCACAGTAGACATTGGGGCGCCTGCAGAGGAACAGCCTGTCATTGAACCAGAAGAAACCCTTGAGCCCGAAGCTTGCTTCACTGAAG
Seq C2 exon
GCTGTGTCCAGAGATTCAAGTGCTGTCAAATCAGCGTGGAAGAAGGAAGAGGGAAACAGTGGTGGAACCTACGGAGGACGTGCTTCCGAATAGTTGAACACAACTGGTTTGAGACCTTCATTGTGTTCATGATTCTCCTGAGTAGTGGTGCCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000064329-'29-34,'29-33,31-34=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.159 A=0.744 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PD(4.2=5.0),PF065128=Na_trans_assoc=PU(61.4=85.1)
A:
PF065128=Na_trans_assoc=FE(17.9=100)
C2:
PF065128=Na_trans_assoc=PD(19.7=84.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACTGTGACTGTGCCCATTG
R:
GGCACCACTACTCAGGAGAAT
Band lengths:
250-371
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types