Special

MmuINT0146136 @ mm9

Intron Retention

Gene
ENSMUSG00000026791 | Slc2a8
Description
solute carrier family 2, (facilitated glucose transporter), member 8 [Source:MGI Symbol;Acc:MGI:1860103]
Coordinates
chr2:32836881-32837403:-
Coord C1 exon
chr2:32837241-32837403
Coord A exon
chr2:32837088-32837240
Coord C2 exon
chr2:32836881-32837087
Length
153 bp
Sequences
Splice sites
5' ss Seq
GGGGTGAGC
5' ss Score
5.97
3' ss Seq
AGCCCGTCCCGGGTCCCCAGGCC
3' ss Score
7.09
Exon sequences
Seq C1 exon
GACTCCCCGCGGCCGCCGGGTCTTCCTCGCTTCCTTCGCCGCCGCTCTGGGACCCCTCAGCTTCGGCTTCGCGCTCGGCTACAGCTCCCCCGCCATCCCCAGCCTGCGGCGCACCGCACCCCCGGCCCTGCGCCTCGGAGACAATGCGGCCTCCTGGTTCGGG
Seq A exon
GTGAGCCCTCTGGGGAGTCCTGGGTCCCCCACTCTCTGCCGCACCCCAGGATCCTCCTCATTCTCTTTCCTCTGAGACTAGGGGGCGTGGGGTGGAAGGATCGTGGGCCATGGCCCCTGGTGGCCTCCTCTTCAGCCCGTCCCGGGTCCCCAG
Seq C2 exon
GCCGTCGTGACCCTGGGCGCTGCTGCAGGGGGCATACTGGGCGGCTGGCTCCTGGACCGTGCAGGGCGCAAGCTGAGCCTCTTGCTCTGCACCGTGCCCTTCGTGACTGGCTTTGCTGTCATCACCGCGGCCCGGGATGTGTGGATGCTGCTCGGAGGCCGCCTCCTCACCGGCCTTGCCTGCGGAGTCGCCTCACTAGTGGCACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026791-Slc2a8:NM_019488:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0008319=Sugar_tr=PU(16.5=80.0)

							
A:
NA

							
C2:
PF0008319=Sugar_tr=FE(15.2=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000028129





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000108817, ENSMUSP00000127486
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr9:130159818-130160183 
ALTERNATIVE
HsaINT0152365
(SLC2A8)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr11:98162048-98162301 
ALTERNATIVE
BtaINT0135170
(SLC2A8)
Chicken
(galGal4)
chr17:6939831-6939910 
ALTERNATIVE
GgaINT0126009
(SLC2A6)
Chicken
(galGal3)
chr17:7612257-7612336 
ALTERNATIVE
GgaINT0126009
(F1NAR8_CHICK)
Zebrafish
(danRer10)
chr5:65293914-65294065 
LOW PSI
DreINT0150531
(slc2a8)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTCTGGGACCCCTCAGCTTC

				
R: 
GGTGATGACAGCAAAGCCAGT

				
Band lengths: 
245-398

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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