BtaEX6016500 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000018010 | ABCA4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:HGNC Symbol;Acc:HGNC:34]
Coordinates
chr3:49655692-49656420:+
Coord C1 exon
chr3:49655692-49655797
Coord A exon
chr3:49655927-49656001
Coord C2 exon
chr3:49656251-49656420
Length
75 bp
Sequences
Splice sites
3' ss Seq
TGTTTTTTATGGCTTTCTAGGGC
3' ss Score
9.83
5' ss Seq
AAGGTATTG
5' ss Score
7.76
Exon sequences
Seq C1 exon
GTATGGAGGAATTTCTGTCGGAGGAAAGCTCCCAGCTCCCCCCTTCACTGGAGAAGCACTTGTTGGATTTTTAAGTGACCTTGGCCAGTTAATGAATGTGAGCGGG
Seq A exon
GGCCCTATGACCAGAGAGGCTGCTAAAGAAATGCCTGCTTTCCTTAAACAACTAGAAACTGAAGACAATATTAAG
Seq C2 exon
GTGTGGTTTAACAACAAAGGTTGGCATGCTCTGGTCAGCTTCCTCAACGTGGCCCACAACGCCATCTTACGGGCTAGCCTGCACAAGGACAAGAACCCCGAGGAGTATGGCATCACCGTCATAAGCCAGCCCTTGAACCTGACCAAGGAGCAGCTCTCTGAGATCACAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000018010-'41-34,'41-33,42-34=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=0.040 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=PU(7.0=63.9)
A:
PF126982=ABC2_membrane_3=FE(7.3=100)
C2:
PF126982=ABC2_membrane_3=FE(17.1=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCTTCACTGGAGAAGCACT
R:
TACTCCTCGGGGTTCTTGTCC
Band lengths:
174-249
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000567; ELM sequence: MNVSGG; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]