MmuEX6073799 @ mm10
Exon Skipping
Gene
ENSMUSG00000028125 | Abca4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424]
Coordinates
chr3:122147198-122147899:+
Coord C1 exon
chr3:122147198-122147303
Coord A exon
chr3:122147431-122147505
Coord C2 exon
chr3:122147730-122147899
Length
75 bp
Sequences
Splice sites
3' ss Seq
CGTTTGCTGTGCTGTTCAAGGGT
3' ss Score
6.08
5' ss Seq
AAGGTACCT
5' ss Score
8.49
Exon sequences
Seq C1 exon
GTATGGAGGAATTTCCATCGGAGGAAAACTCCCTGCTATCCCCATCAGCGGGGAAGCACTTGTTGGCTTTCTAAGTGGCCTTGGCCAGATGATGAACGTGAGCGGG
Seq A exon
GGTCCTGTCACCAGGGAGGCCTCCAAAGAAATGTTAGATTTCCTCAAACATCTTGAAACCACAGACAACATTAAG
Seq C2 exon
GTATGGTTTAACAACAAGGGCTGGCATGCCCTGGTCAGCTTTCTGAATGTGGCTCACAACGCCATCTTACGGGCCAGCCTGCCCAGGGACAGGGACCCTGAGGAGTATGGAATCACTGTCATCAGCCAGCCTCTGAACCTGACCAAGGAGCAGCTCTCGGACATCACAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028125-'63-64,'63-63,64-64
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=0.080 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF126982=ABC2_membrane_3=PU(10.9=80.0)
C2:
PF126982=ABC2_membrane_3=FE(18.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTAAGTGGCCTTGGCCAGATG
R:
GTTCAGAGGCTGGCTGATGAC
Band lengths:
174-249
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000567; ELM sequence: MNVSGG; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types