Special

DmeEX0004618 @ dm6

Exon Skipping

Gene
FBgn0026430 | Grip84
Description
The gene Gamma-tubulin ring protein 84 is referred to in FlyBase by the symbol DmelGrip84 (CG3917, FBgn0026430). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:19559431..19565764. Its molecular function is described by: gamma-tubulin binding; microtubule minus-end binding. It is involved in the biological process described with 10 unique terms, many of which group under: cellular process; cellular component organization; cellular component assembly; microtubule cytoskeleton organization; reproductive process. 12 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; cell cycle defective; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
Coordinates
chrX:19561340-19563013:-
Coord C1 exon
chrX:19562692-19563013
Coord A exon
chrX:19562411-19562509
Coord C2 exon
chrX:19561340-19561795
Length
99 bp
Sequences
Splice sites
3' ss Seq
GCTAATCCCCACCTTCGCAGATC
3' ss Score
6.8
5' ss Seq
CAGGTATTG
5' ss Score
8.35
Exon sequences
Seq C1 exon
GATTTGGAAGGAAAACTCGATTGCCAGGCAGTTCGAGCCGCAGGCGGCTAGTCTCTATCGAGCGGCGTTCACTCTGCGCCAGCGTATGATGAATGCCATCCAGAACCTGGAGTACTACATGATGATCGAGATCATCGAGCCCAACTGGCACATTTTCATTGAAAAGATGAAGACGGTGGAGAACGTGGATAACGTTCTGCGTCTCCACCAGGACTTCCTCGACTCGTGCCTTAAGAACTGCATGCTGACCGAGTCGTCGCATCTGAATCGTTCGATCTTCAAGCTCTGCAAGATCTGCCTGAAGTACTGCGAGTTCATCCAG
Seq A exon
ATCACGCAGCGTTACTTTCAGGACGCTGAGCTCAGGTCGATGGTACGTGATAGCGCGGACAGCTCCGAATCCGAACAGGAGAGCCTGCACTGCCCACAG
Seq C2 exon
ATTGAGACCCCGTTGGATCCGACAGATACGTTTTCGGAGCGGGTTAGGCGCTTTGATCTGGAATTTACCCAACTGCTGATATCGTTCCTCAAGCAGATCAACAGCATGGCGAAGAAGAACACCGCCGATTGCTTCATGAATCTGGTGCACCGCATCAACTTCAATGCCTTCTACACCGATCAAATGGACAAGATGTGTGTAGAGGATGCCATTGGCTAAGCCAGCACGTCTAGAGGAAAGGATGTGGATGTGGATGTGGATGTGGACGTGGAAACGGAAACGGAAAAGACAAGAACAAAGTATTAGATAAATGAATTTCATAATCACAAGCGCACATTTACCATCATTCCCCACGCATGTCTTCTCATTTGCCATCCAACAAAGCGCACCAATTGTTACCCGTTTAGTTATACAAATTCGAATATGTATGAACCAATAAACCAATTAAAATGTCCT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0026430_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.242 C2=0.000
Domain overlap (PFAM):

C1:
PF041308=Spc97_Spc98=PD(15.6=75.0)
A:
NO
C2:
PF041308=Spc97_Spc98=PD(15.6=66.9)


Main Inclusion Isoform:
FBpp0074544


Main Skipping Isoform:
FBpp0290523


Other Inclusion Isoforms:
FBpp0074545, FBpp0290522


Other Skipping Isoforms:
FBpp0074546, FBpp0310187
Associated events
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTCCTCGACTCGTGCCTTA
R:
CCAGATCAAAGCGCCTAACCC
Band lengths:
171-270
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)