DmeEX6002350 @ dm6
Exon Skipping
Gene
FBgn0030571 | CG14414
Description
This gene is referred to in FlyBase by the symbol DmelCG14414 (FBgn0030571). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is X:14580600..14582174. Its molecular function is described by: mRNA binding; RNA binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; short lived; viable; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chrX:14580740-14581674:+
Coord C1 exon
chrX:14580740-14580846
Coord A exon
chrX:14580919-14581039
Coord C2 exon
chrX:14581582-14581674
Length
121 bp
Sequences
Splice sites
3' ss Seq
ATTTGCATTGCCCCCTATCGGTT
3' ss Score
0.79
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
GCCGGAACGAGTGGGTCGGGTGGCTTAAGCGGCGGCGGCGGCGGCGGTGGAAACCCCGAGGAGGCGCGTCGCATCTGGGTTGGGAATCTGGACTCACGGATCACCGA
Seq A exon
GTTTCAACTCCTCAAACTGATGCAAAAATGCGGCGCCATCGAGAAGTTCGACATGCTGTTCCACAAGGGCGGTCCCATGGTGGGACAATCCAGGGGCTACGCCTTCGTCACCTTTGCGCAG
Seq C2 exon
AACGAGGGAGCCACCAATGCGCTACTGAAACTGGACGGAACCAGCGTGGGAAATCGCTCGATAGCCGTGCGTTTGGCCAAGAACATTAAATAT
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0030571-'1-6,'1-2,2-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.569 A=0.009 C2=0.137
Domain overlap (PFAM):
C1:
PF0007617=RRM_1=PU(14.9=30.6)
A:
PF0007617=RRM_1=FE(54.1=100)
C2:
PF0007617=RRM_1=PD(53.8=67.7)
Main Inclusion Isoform:
FBpp0292380
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0073747, FBpp0073749, FBpp0308546
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg19)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTGGGTCGGGTGGCTTAAG
R:
AATGTTCTTGGCCAAACGCAC
Band lengths:
186-307
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)