DreEX0007294 @ danRer10
Exon Skipping
Gene
ENSDARG00000075924 | RAPGEF4 (1 of 2)
Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr6:6702706-6718967:+
Coord C1 exon
chr6:6702706-6702848
Coord A exon
chr6:6705449-6705537
Coord C2 exon
chr6:6718821-6718967
Length
89 bp
Sequences
Splice sites
3' ss Seq
TGTGTTTGTTTGCCTTGCAGTGT
3' ss Score
10.05
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
Exon sequences
Seq C1 exon
GCCAGCTGAACGCTCGGGAGAAGACGTGGACATCATTCTGGCTCGGCTGAAGGGTGTGAAGGCCTTCGAGAAGTTTCATCCTAACCTGCTGCAGCAGATCTGCATGTGTGGCTTTTATGAGTACCTAGAGAAAGGCATCACCT
Seq A exon
TGTATCGACAGGGTGACATCGGCACCAGCTGGTACGCCGTTCTGTCTGGATCTCTGGACGTCAAAGTGTCTGAAACAGCCAACCATCAG
Seq C2 exon
GATGCTGTAACAATCTGTACTTTGGGAGTGGGAACAGCATTCGGGGAGTCAATTCTGGACAACACTCCTCGACATGCCACGATTGTCAGCCGAGAGAACAGTGAACTTCTGCGCATCGAGCAGAGGGAGTTCAAAACCCTGTGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000075924-'2-2,'2-1,3-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.020
Domain overlap (PFAM):
C1:
PF0002724=cNMP_binding=PU(9.8=18.4)
A:
PF0002724=cNMP_binding=FE(31.5=100)
C2:
PF0002724=cNMP_binding=FE(52.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTGTGAAGGCCTTCGAGAAG
R:
TGACAATCGTGGCATGTCGAG
Band lengths:
179-268
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]