DreEX0064504 @ danRer10

Exon Skipping

Gene

ENSDARG00000086819 | scn1a

Description

sodium channel, voltage-gated, type I, alpha [Source:ZFIN;Acc:ZDB-GENE-040426-751]

Coordinates

chr9:50257283-50264766:-

Coord C1 exon

chr9:50264625-50264766

Coord A exon

chr9:50259642-50259848

Coord C2 exon

chr9:50257283-50257534

Length

207 bp

Sequences

Splice sites

3' ss Seq

ATTGTGGATTTTTTTTACAGACT

3' ss Score

6.73

5' ss Seq

GAGGTCTGT

5' ss Score

5.39

Exon sequences

Seq C1 exon

GCAGTGTCCAGAGGGATATACGTGTTTAAAAGCAGGTAACAATCCAGATTATGGTTACACAAGCTTTGATTCGTTCGGCTGGGCTTTCCTTTCCTTGTTCAGACTGATGACTCAAGACTTCTGGGAGAATCTTTACCAACAG

Seq A exon

ACTCTTCGGGCCGCTGGGAAAACCTATATGATTTTTTTCGTGCTGGTCATTTTCTTGGGATCCTTCTACCTGGTGAACCTCATCCTGGCTGTAGTCGCCATGGCATACGACGAACAGAATCAAGCCACGATCGACGAGGCTTTGAAAAAAGAGGAAGAGTTCAACGCCATGCTTGAGCAGATCACGAGACAGGAGCAGGAAGCTGAG

Seq C2 exon

GCTGCAGCCGAACAGTCCAAGTGTGAGGGTCTCAGTGGAGAAAAGACGGACAGTTCCTCGGACGCCTCCAAACTCAGCTCCAAAAGTGCCAAAGAGCGACGCAACCGCAAGAAAAAGAGACAACACCAGGGGGAAAGCGAGAAAGAGGAGGATTCCATAAAAGAGGGAAATGACAGAAAGCCCAACTTCACTTTTGCAGTGGATGGAAAGATCCGGCGATCACGGGACAGATCATACACGTCTCCACGTCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSDARG00000086819-'15-15,'15-14,16-15

Average complexity

S

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.130 C2=1.000

Domain overlap (PFAM):

C1:

PF146251=Lustrin_cystein=PD(47.4=37.5),PF0052026=Ion_trans=FE(48.0=100),PF0382411=NicO=PU(17.3=47.9),PF0253517=Zip=PU(14.4=47.9),PF057587=Ycf1=PU(11.2=41.7),PF0479111=LMBR1=PU(9.0=27.1)

A:

PF0052026=Ion_trans=PD(32.7=45.7),PF0382411=NicO=FE(51.9=100),PF0253517=Zip=FE(43.1=100),PF057587=Ycf1=FE(38.5=100),PF0479111=LMBR1=FE(47.6=100),PF0293211=Neur_chan_memb=PU(34.2=90.0),PF074236=DUF1510=PU(49.6=88.6)

C2:

PF0382411=NicO=PD(30.1=47.1),PF0253517=Zip=PD(41.9=78.8),PF057587=Ycf1=FE(46.9=100),PF0479111=LMBR1=PD(42.8=72.9),PF0293211=Neur_chan_memb=FE(45.7=100),PF074236=DUF1510=PD(49.6=72.9),PF119333=DUF3451=PU(29.0=75.3)

Main Inclusion Isoform:

ENSDARP00000138437