DreEX0064511 @ danRer10

Exon Skipping

Gene

ENSDARG00000086819 | scn1a

Description

sodium channel, voltage-gated, type I, alpha [Source:ZFIN;Acc:ZDB-GENE-040426-751]

Coordinates

chr9:50249698-50257534:-

Coord C1 exon

chr9:50257283-50257534

Coord A exon

chr9:50255168-50255536

Coord C2 exon

chr9:50249698-50249818

Length

369 bp

Sequences

Splice sites

3' ss Seq

GGCTTGTTTTTTTTCTTCAGTCC

3' ss Score

7.9

5' ss Seq

TGTGTAAGG

5' ss Score

4.52

Exon sequences

Seq C1 exon

GCTGCAGCCGAACAGTCCAAGTGTGAGGGTCTCAGTGGAGAAAAGACGGACAGTTCCTCGGACGCCTCCAAACTCAGCTCCAAAAGTGCCAAAGAGCGACGCAACCGCAAGAAAAAGAGACAACACCAGGGGGAAAGCGAGAAAGAGGAGGATTCCATAAAAGAGGGAAATGACAGAAAGCCCAACTTCACTTTTGCAGTGGATGGAAAGATCCGGCGATCACGGGACAGATCATACACGTCTCCACGTCAG

Seq A exon

TCCCCCTTGAGTTTTCAGGGTTCCCTCCTCACTCCTCGTCGGGACAGCAAAGCGAGCGTCTTCAGTTTCCGTGGACGAATTCATTCAGATAACAACTACGCCGACGACGAGCAGAGCATGTTTGAGGAGACGGGCAGCCGAAGAGACTCTCTGTTTCTTCCCACTCGACCCGAGCGTCTTTTCAGCAACGTTAGCAAAAGCAGTCTGACTCCGCACTTACTGCTGCCTTCTAACGGGAAAGCACGCTACGTGGATGACAGCAACGGGATGGTGATGGTGACAAGTGGAGCATCTGCACCAAACTCCCCTGTCATAGCCCTGAATACACCAGAAGTTTCCCGAAAAAGAGCCATGTTTGACGACACTTGT

Seq C2 exon

GCAGACTCAGATGACGAACGCAGAAGCAGATGTAATTCACAGAACTTTTCGAAGGCTTATCGGCAGTCTATGAGAGAGAGAGCTTTGAGTGTAGCAAGTGGCAGCAACAACCCTGCTGAAT

VastDB Features

Vast-tools module Information

Secondary ID

ENSDARG00000086819_CASSETTE1

Average complexity

S

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=1.000 A=0.481 C2=0.006

Domain overlap (PFAM):

C1:

PF0382411=NicO=PD(30.1=47.1),PF0253517=Zip=PD(41.9=78.8),PF057587=Ycf1=FE(46.9=100),PF0479111=LMBR1=PD(42.8=72.9),PF0293211=Neur_chan_memb=FE(45.7=100),PF074236=DUF1510=PD(49.6=72.9),PF119333=DUF3451=PU(29.0=75.3)

A:

PF119333=DUF3451=FE(55.4=100)

C2:

PF119333=DUF3451=PD(15.3=82.9)

Main Inclusion Isoform:

ENSDARP00000138437