DreEX6065227 @ danRer10
Exon Skipping
Gene
ENSDARG00000062686 | megf11
Description
multiple EGF-like-domains 11 [Source:ZFIN;Acc:ZDB-GENE-060503-252]
Coordinates
chr18:19224183-19251458:-
Coord C1 exon
chr18:19251246-19251458
Coord A exon
chr18:19239651-19239825
Coord C2 exon
chr18:19224183-19224303
Length
175 bp
Sequences
Splice sites
3' ss Seq
CTTTCTTTCTCTTTTTTCAGCTG
3' ss Score
12.69
5' ss Seq
ACAGTGAGT
5' ss Score
8.34
Exon sequences
Seq C1 exon
GTGCCAGGAAGAGTGTCCGGTTGGCACCTATGGACCCCAGTGCACCCTCCATTGTGACTGTCAGAATGGGGCAAAGTGTTACCACATCAATGGAGCTTGTTTGTGCGATACGGGATTCAAAGGGCACCACTGCCAGGATAGATTCTGTCCACCAGGCCTTTACGGTCTCATCTGTGACAAATACTGCCCCTGTAATTCCACCAACACAATCAG
Seq A exon
CTGTCACCCCTTGACTGGTGAATGCTCATGTACGGCGGGATGGACGGGCCTATATTGTAACGAGACCTGTCCCCCGGGCTACTATGGAGAAGGATGTGGAGTGCCGTGCCAGTGTGCTAATGGAGCCGACTGCCACAGTCTCACCGGGGCCTGTATCTGTGCCCCGGGCTACACA
Seq C2 exon
GGAGATGACTGTTCCCAAACCTGCCCATCTGGACTATTTGGGACTAACTGCACTTCCATTTGCCACTGCCACAACCAGGCGTCCTGCTCACCAATCGATGGCTCCTGTATCTGTAAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062686-'7-9,'7-8,8-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(7.7=1.4),PF0005319=Laminin_EGF=PU(18.8=12.5)
A:
PF0005319=Laminin_EGF=PD(79.2=64.4),PF126612=hEGF=PU(61.5=13.6)
C2:
PF126612=hEGF=PD(23.1=7.3),PF0005319=Laminin_EGF=PU(43.5=48.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACCCTCCATTGTGACTGTC
R:
TTGTGGCAGTGGCAAATGGAA
Band lengths:
246-421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]