HsaEX0038727 @ hg19
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66223161-66257458:-
Coord C1 exon
chr15:66257246-66257458
Coord A exon
chr15:66249885-66250059
Coord C2 exon
chr15:66223161-66223281
Length
175 bp
Sequences
Splice sites
3' ss Seq
CCCTTCTCTCATCTGTGCAGCTG
3' ss Score
10.42
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
Exon sequences
Seq C1 exon
GTGCCAAGAGGAGTGCCCCTTCGGGTCCTTCGGCTTCCAGTGCTCACAGCACTGTGACTGCCACAATGGGGGGCAGTGTTCACCCACCACGGGTGCCTGCGAGTGTGAGCCTGGCTACAAGGGCCCACGCTGCCAGGAGCGACTGTGCCCGGAGGGCCTGCATGGCCCAGGCTGCACCCTGCCCTGCCCCTGTGACGCTGACAACACCATCAG
Seq A exon
CTGCCACCCAGTAACTGGAGCTTGTACCTGCCAGCCAGGCTGGTCTGGTCACCACTGCAATGAATCCTGCCCTGTTGGCTACTATGGCGATGGCTGCCAGCTGCCTTGCACCTGTCAGAATGGCGCCGACTGCCACAGCATCACTGGGGGCTGCACTTGTGCTCCGGGCTTCATG
Seq C2 exon
GGAGAGGTCTGTGCCGTTTCCTGTGCAGCAGGGACCTATGGCCCCAACTGCTCGTCCATCTGTAGCTGTAACAATGGTGGCACCTGCTCCCCAGTAGATGGCTCCTGTACCTGCAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'14-16,'14-15,15-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(42.6=27.8),PF126612=hEGF=WD(100=18.1),PF0005319=Laminin_EGF=PU(20.4=13.9)
A:
PF0005319=Laminin_EGF=PD(77.6=64.4)
C2:
PF079748=EGF_2=PU(77.4=58.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCGGCTTCCAGTGCTCAC
R:
AGCTACAGATGGACGAGCAGT
Band lengths:
253-428
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)