HsaEX0038727 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65930823-65965120:-
Coord C1 exon
chr15:65964908-65965120
Coord A exon
chr15:65957547-65957721
Coord C2 exon
chr15:65930823-65930943
Length
175 bp
Sequences
Splice sites
3' ss Seq
CCCTTCTCTCATCTGTGCAGCTG
3' ss Score
10.42
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
Exon sequences
Seq C1 exon
GTGCCAAGAGGAGTGCCCCTTCGGGTCCTTCGGCTTCCAGTGCTCACAGCACTGTGACTGCCACAATGGGGGGCAGTGTTCACCCACCACGGGTGCCTGCGAGTGTGAGCCTGGCTACAAGGGCCCACGCTGCCAGGAGCGACTGTGCCCGGAGGGCCTGCATGGCCCAGGCTGCACCCTGCCCTGCCCCTGTGACGCTGACAACACCATCAG
Seq A exon
CTGCCACCCAGTAACTGGAGCTTGTACCTGCCAGCCAGGCTGGTCTGGTCACCACTGCAATGAATCCTGCCCTGTTGGCTACTATGGCGATGGCTGCCAGCTGCCTTGCACCTGTCAGAATGGCGCCGACTGCCACAGCATCACTGGGGGCTGCACTTGTGCTCCGGGCTTCATG
Seq C2 exon
GGAGAGGTCTGTGCCGTTTCCTGTGCAGCAGGGACCTATGGCCCCAACTGCTCGTCCATCTGTAGCTGTAACAATGGTGGCACCTGCTCCCCAGTAGATGGCTCCTGTACCTGCAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'25-36,'25-33,26-36
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PD(3.2=1.4),PF0005319=Laminin_EGF=WD(100=56.9),PF0005319=Laminin_EGF=PU(20.4=13.9)
A:
PF0005319=Laminin_EGF=PD(77.6=64.4)
C2:
PF079748=EGF_2=PU(77.4=58.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCGGCTTCCAGTGCTCAC
R:
AGCTACAGATGGACGAGCAGT
Band lengths:
253-428
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development