DreEX6071218 @ danRer10
Exon Skipping
Gene
ENSDARG00000063713 | SYNGAP1 (1 of 2)
Description
synaptic Ras GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:11497]
Coordinates
chr19:258113-259457:+
Coord C1 exon
chr19:258113-258234
Coord A exon
chr19:258851-259004
Coord C2 exon
chr19:259359-259457
Length
154 bp
Sequences
Splice sites
3' ss Seq
GTGTGTGTGTGTGTGTGCAGGAC
3' ss Score
10.03
5' ss Seq
GAGGTGCTG
5' ss Score
2.64
Exon sequences
Seq C1 exon
AGTTTTCTCAGCCGCCGCTTGAAAGGATCAATTAAACGAGCAAAGAGTCAACCCAAACTCGACCGCACGGGAAGCTTCCGCCACATGATTCTCCCACGATTCCGCAGTGCTGACCAGGAGAG
Seq A exon
GACGCGTCTGATGCAGAGCTTTAAGGAGTCTCACTCTCATGAGTCTCTGCTGTCTCCGAGCAGCGCGGCCGAGGCTCTGGACCTCACGCTGGACGAGGACGCCATCATCAAACCCGTCCACTCCAGCATCCTCGGCCAGGAGTACTGCTTCGAG
Seq C2 exon
GTGACCACGGCGTCAGGAACCAAGTGTTTCGCCTGCCGCTCCGCTGCTGAGAGAGACAAATGGATCGAGAATCTGCAGCGAGCCGTCAAACCAAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000063713-'6-8,'6-5,8-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.732 A=0.355 C2=0.085
Domain overlap (PFAM):
C1:
PF0016924=PH=PU(19.6=48.8)
A:
PF0016924=PH=FE(50.0=100)
C2:
PF0016924=PH=PD(28.4=87.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTCTCAGCCGCCGCTTG
R:
CTTGTTTGGTTTGACGGCTCG
Band lengths:
219-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]