HsaEX0035434 @ hg19
Exon Skipping
Gene
ENSG00000090661 | LASS4
Description
ceramide synthase 4 [Source:HGNC Symbol;Acc:23747]
Coordinates
chr19:8275590-8319500:+
Coord C1 exon
chr19:8275590-8275746
Coord A exon
chr19:8315960-8316133
Coord C2 exon
chr19:8319383-8319500
Length
174 bp
Sequences
Splice sites
3' ss Seq
ACTGGAACCTGTGTCCACAGAAT
3' ss Score
6.43
5' ss Seq
GAGGTGAGT
5' ss Score
10.03
Exon sequences
Seq C1 exon
GAGCAGCTGCTGTGAATAAACACAGAAGTGGAGCTGGGGGACTGATTAGAAGCCTCATTCAGTGCACCTGGGCCCCAGCAGGCCCAGCCAGGCGTGGAGGAAGAGGCATTGAGGACTTTCCTTACCTGTTTTTCCAGCTCACCCACTGCCAGCAGAG
Seq A exon
AATGCTGTCCAGTTTCAACGAGTGGTTTTGGCAGGACAGGTTCTGGTTACCACCCAATGTCACGTGGACAGAGCTAGAAGACCGGGATGGCCGTGTCTACCCCCACCCCCAGGACTTGTTGGCAGCCCTGCCCCTGGCGCTGGTCCTCCTGGCCATGCGCCTTGCCTTTGAGAG
Seq C2 exon
ATTCATTGGCCTGCCCCTGAGCCGGTGGCTGGGTGTGAGGGATCAGACCAGGAGGCAAGTGAAGCCCAACGCCACGCTGGAGAAACACTTCCTCACGGAAGGGCACAGGCCCAAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000090661_MULTIEX1-4/4=C1-C2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show structural model
Features
Disorder rate (Iupred):
C1=NA A=0.017 C2=0.025
Domain overlap (PFAM):
C1:
NA
A:
PF067288=PIG-U=PU(13.7=36.2)
C2:
PF0004624=Homeobox=PU(45.6=65.0),PF067288=PIG-U=FE(25.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGCTGCTGTGAATAAACACA
R:
AGGAAGTGTTTCTCCAGCGTG
Band lengths:
248-422
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)