HsaEX0038085 @ hg19
Exon Skipping
Gene
ENSG00000204406 | MBD5
Description
methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:20444]
Coordinates
chr2:149215772-149221488:+
Coord C1 exon
chr2:149215772-149216440
Coord A exon
chr2:149220151-149220253
Coord C2 exon
chr2:149221308-149221488
Length
103 bp
Sequences
Splice sites
3' ss Seq
TTTTTAAACTATTTTTACAGTCC
3' ss Score
7.15
5' ss Seq
AAGGTAACC
5' ss Score
9.24
Exon sequences
Seq C1 exon
AATAGAGATTGTCTTAGTACAACATCAAGGTTCAAGACAAATGTTGAACTAAAAACTTTACACTCCCCACCCCCACTTCAGACAGGTACCAGCATTGGTGAATTATGATTTTCCTTAGTCAGAAGCACTCATTTTTACCCATGTAGACCATCCTTAGGAATTAAATATTGGTTATTTAATGTAGATTATAATGGGAAGCTGATTTTTTTCACAATGGCATATTTCAAGGACTTGGTTCCAAACTGAGCTGAAGCTTCCCAATGCGTTTTGTACAGTCTGGGAAAAACTGTGCTGCACTGGCCCACTTTTGAAGGCCATCATGCTCTGTAATATAAGGATATCATCTTATTGCTGATATCTTTGGAGAGTCCCTAGCAGACACAGAAAATGAATGGAGGCAAAGAGTGTGACGGAGGGGACAAGGAAGGAGGTCTTCCAGCTATACAAGTTCCTGTGGGTTGGCAGCGTCGTGTGGATCAAAATGGAGTGCTTTATGTCAG
Seq A exon
TCCCAGTGGGTCTTTGTTATCTTGCTTGGAGCAGGTTAAAACATACCTGCTTACTGATGGAACATGCAAGTGTGGCTTGGAATGTCCTCTTATTCTTCCCAAG
Seq C2 exon
GTATTTAATTTTGATCCTGGAGCTGCTGTGAAACAGAGAACCGCAGAAGATGTTAAGGCAGATGAAGATGTCACAAAGCTATGCATACATAAAAGAAAAATTATTGCAGTGGCCACACTTCATAAAAGCATGGAAGCCCCACATCCTTCTCTGGTGCTCACCAGTCCCGGAGGAGGAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204406-'23-26,'23-25,25-26
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.184 A=0.000 C2=0.328
Domain overlap (PFAM):
C1:
PF0142914=MBD=PU(29.9=52.6)
A:
PF0142914=MBD=FE(50.7=100)
C2:
PF0142914=MBD=PD(16.4=18.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGAAAAACTGTGCTGCACT
R:
GTTTCACAGCAGCTCCAGGAT
Band lengths:
257-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)