HsaEX0052107 @ hg38
Exon Skipping
Gene
ENSG00000116191 | RALGPS2
Description
Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:HGNC:30279]
Coordinates
chr1:178821612-178877635:+
Coord C1 exon
chr1:178821612-178821704
Coord A exon
chr1:178833424-178833550
Coord C2 exon
chr1:178877498-178877635
Length
127 bp
Sequences
Splice sites
3' ss Seq
TTTTTCTGTTTGTTTTTTAGTTA
3' ss Score
11.12
5' ss Seq
TAGGTGAGT
5' ss Score
8.83
Exon sequences
Seq C1 exon
AAACTGTATGAGCTGAATAACCTTCATGCACTTATGGCAGTGGTTTCTGGCCTACAGAGTGCCCCAATTTTCAGGTTGACTAAAACATGGGCG
Seq A exon
TTATTAAGTCGAAAAGACAAAACTACCTTTGAAAAATTAGAATATGTAATGAGTAAAGAAGATAACTACAAAAGACTCAGAGACTATATAAGTAGCTTAAAGATGACACCTTGCATTCCCTATTTAG
Seq C2 exon
GTATCTATTTGTCAGATTTAACATACATCGATTCAGCATACCCATCAACTGGCAGCATTCTAGAAAATGAGCAAAGATCAAATTTAATGAATAATATCCTTCGAATAATTTCTGATTTACAGCAGTCTTGTGAATATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000116191_MULTIEX1-6/10=5-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(12.9=100)
A:
PF0061714=RasGEF=FE(18.0=100)
C2:
PF0061714=RasGEF=PD(18.1=74.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTGTATGAGCTGAATAACCTTCA
R:
TTCACAAGACTGCTGTAAATCAGA
Band lengths:
226-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development