HsaEX6042190 @ hg38
Exon Skipping
Gene
ENSG00000118898 | PPL
Description
periplakin [Source:HGNC Symbol;Acc:HGNC:9273]
Coordinates
chr16:4885094-4890921:-
Coord C1 exon
chr16:4890728-4890921
Coord A exon
chr16:4890184-4890334
Coord C2 exon
chr16:4885094-4885113
Length
151 bp
Sequences
Splice sites
3' ss Seq
TGAACGCTTTGCCTTGACAGGGC
3' ss Score
7.36
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
GCCATGGCCTGTGAGTTACAGGCCCAGAAGTCCCTCCTGGGTGAGGTGGAGCAGAACTTGCAGGCGGCCAAGCAGTGCTCGAGCACACTGGCCAGCCGCTTCCAGGAGCACTGTCCGGACCTGGAGCGCCAGGAGGCCGAGGTGCACAAGCTGGGCCAGCGTTTCAACAACCTGCGCCAGCAGGTGGAACGCAG
Seq A exon
GGCGCAGAGCCTACAGAGCGCCAAGGCAGCCTACGAGCACTTCCACCGCGGCCATGACCACGTGCTGCAGTTCCTAGTCAGCATCCCCAGTTACGAGCCCCAGGAGACAGACAGCCTCAGCCAGATGGAGACCAAGCTGAAGAACCAGAAG
Seq C2 exon
ACCCCAAGGCGGAAAGTGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000118898_MULTIEX1-15/18=14-C2
Average complexity
C3
Mappability confidence:
94%=94=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.169 A=0.357 C2=NA
Domain overlap (PFAM):
C1:
PF0026115=Tropomyosin=PU(42.5=83.1)
A:
PF0026115=Tropomyosin=FE(39.4=100)
C2:
NA
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCATGGCCTGTGAGTTACA
R:
TTCACTTTCCGCCTTGGGGT
Band lengths:
214-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains