HsaEX6067421 @ hg38
Exon Skipping
Gene
ENSG00000166987 | MBD6
Description
methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:HGNC:20445]
Coordinates
chr12:57524280-57525115:+
Coord C1 exon
chr12:57524280-57524416
Coord A exon
chr12:57524720-57524822
Coord C2 exon
chr12:57524953-57525115
Length
103 bp
Sequences
Splice sites
3' ss Seq
CTGACCCTGTCCTCTCGCAGTCC
3' ss Score
10.16
5' ss Seq
AAGGTCAGA
5' ss Score
6.8
Exon sequences
Seq C1 exon
GCACGCGGGAGCTGATTACACACAATGAATGGGGGCAATGAGAGCAGTGGAGCAGACAGAGCTGGGGGCCCTGTGGCCACATCTGTCCCCATCGGCTGGCAGCGCTGTGTGCGAGAGGGTGCTGTGCTCTACATCAG
Seq A exon
TCCAAGTGGCACAGAGCTGTCTTCCTTGGAGCAAACCCGGAGCTACCTCCTCAGCGATGGGACCTGCAAGTGCGGTCTGGAGTGTCCACTTAATGTCCCCAAG
Seq C2 exon
GTTTTCAACTTTGACCCTTTGGCCCCGGTGACCCCGGGTGGGGCTGGGGTGGGGCCAGCATCAGAGGAGGACATGACCAAGCTGTGCAACCACCGGCGGAAAGCTGTTGCTATGGCAACTCTGTACCGCAGCATGGAGACCACCTGCTCACACTCTTCTCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166987-'7-19,'7-18,12-19
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.434 A=0.117 C2=0.606
Domain overlap (PFAM):
C1:
PF0142914=MBD=PU(43.3=68.4)
A:
PF0142914=MBD=PD(55.0=94.3)
C2:
PF0142914=MBD=PD(15.3=20.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGAGAGCAGTGGAGCAGACA
R:
AAGAGTGTGAGCAGGTGGTCT
Band lengths:
257-360
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains