HsaEX6069478 @ hg19
Exon Skipping
Gene
ENSG00000122966 | CIT
Description
citron (rho-interacting, serine/threonine kinase 21) [Source:HGNC Symbol;Acc:1985]
Coordinates
chr12:120262969-120272032:-
Coord C1 exon
chr12:120271890-120272032
Coord A exon
chr12:120270575-120270668
Coord C2 exon
chr12:120262969-120263172
Length
94 bp
Sequences
Splice sites
3' ss Seq
TGGTCCTGATTTTCTTACAGAGA
3' ss Score
7.55
5' ss Seq
ATGGTAAAA
5' ss Score
4.79
Exon sequences
Seq C1 exon
GTCATGGAATATCAGCCTGGAGGGGACTTGCTGTCACTTTTGAATAGATATGAGGACCAGTTAGATGAAAACCTGATACAGTTTTACCTAGCTGAGCTGATTTTGGCTGTTCACAGCGTTCATCTGATGGGATACGTGCATCG
Seq A exon
AGACATCAAGCCTGAGAACATTCTCGTTGACCGCACAGGACACATCAAGCTGGTGGATTTTGGATCTGCCGCGAAAATGAATTCAAACAAGATG
Seq C2 exon
GTGAATGCCAAACTCCCGATTGGGACCCCAGATTACATGGCTCCTGAAGTGCTGACTGTGATGAACGGGGATGGAAAAGGCACCTACGGCCTGGACTGTGACTGGTGGTCAGTGGGCGTGATTGCCTATGAGATGATTTATGGGAGATCCCCCTTCGCAGAGGGAACCTCTGCCAGAACCTTCAATAACATTATGAATTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966-'6-7,'6-6,7-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(17.8=100)
A:
PF0006920=Pkinase=FE(11.7=100)
C2:
PF0006920=Pkinase=FE(25.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATCAGCCTGGAGGGGACTTG
R:
AGGAGCCATGTAATCTGGGGT
Band lengths:
179-273
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)