HsaEX6069478 @ hg38
Exon Skipping
Gene
ENSG00000122966 | CIT
Description
citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]
Coordinates
chr12:119784960-119850275:-
Coord C1 exon
chr12:119850174-119850275
Coord A exon
chr12:119832771-119832864
Coord C2 exon
chr12:119784960-119785065
Length
94 bp
Sequences
Splice sites
3' ss Seq
TGGTCCTGATTTTCTTACAGAGA
3' ss Score
7.55
5' ss Seq
ATGGTAAAA
5' ss Score
4.79
Exon sequences
Seq C1 exon
GTTTCATTTTTTGAGGAAGAGCGGAACATATTATCTCGAAGCACAAGCCCGTGGATCCCCCAATTACAGTATGCCTTTCAGGACAAAAATCACCTTTATCTG
Seq A exon
AGACATCAAGCCTGAGAACATTCTCGTTGACCGCACAGGACACATCAAGCTGGTGGATTTTGGATCTGCCGCGAAAATGAATTCAAACAAGATG
Seq C2 exon
GTCTGTTGTGTCGGGTCTGGACTCCCCTGCCAAGACTAGCTCCATGGAAAAGAAACTTCTCATCAAAAGCAAAGAGCTACAAGACTCTCAGGACAAGTGTCACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122966_MULTIEX3-2/25=C1-7
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.477
Domain overlap (PFAM):
C1:
PF115393=DUF3228=FE(30.8=100),PF0006920=Pkinase=FE(34.4=100)
A:
PF0006920=Pkinase=FE(11.7=100)
C2:
NO
Main Skipping Isoform:
ENST00000392521fB12423
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTATCTCGAAGCACAAGCCCG
R:
TGTGACACTTGTCCTGAGAGTCT
Band lengths:
176-270
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains