HsaINT0008883 @ hg19
Intron Retention
Gene
ENSG00000167612 | ANKRD33
Description
ankyrin repeat domain 33 [Source:HGNC Symbol;Acc:13788]
Coordinates
chr12:52283156-52284769:+
Coord C1 exon
chr12:52283156-52283296
Coord A exon
chr12:52283297-52284367
Coord C2 exon
chr12:52284368-52284769
Length
1071 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGC
5' ss Score
6.46
3' ss Seq
CCCCCTGTGCTCCTTCCCAGGTG
3' ss Score
11.37
Exon sequences
Seq C1 exon
GCCACGTGCCTCTAGTGAGTCTCCTGCTCAACTACTATGTGGGCCTGGACCTGGAACGCCGGGACCAGCGGGGGCTCACGGCGTTAATGAAGGCTGCCATGCGGAACCGCTGTGAGTGCGTGGCCACCCTCCTCATGGCAG
Seq A exon
GTGTGCGGGGCCTGGACCGGGGTGTGTGGCCTCCAGTCCCTCCTCCAAGCCTTCCCACCAGACACTAAGTCAGCTGTGATTATTTGCAGAAAGGAGAGAGGTGGAGATGGGGGATCAATCTAGTTCACCTTCCTGGAGGGGGGGGCACATGATTTGGGCTTCGTACAATCAACCAAGTCCTGCTATTGATAGCTCAGACATTGTGTGTGGAGGTCCCAGGAAGGAAAGTGTGGGAGGGGAACCTAGCCCAGCTGGAAAATCTAACACGAAAAAAGGCTGGCATCTGGAACCAGCCCCTGTTCCTAGCTGAGTGGCTTCCCTCTTTGGGCCTCACCAGTATTGTGAGGGTGTTAGCTTTCCCTGGGACTACCTCCAACTCTGACAAGCCAGGCTTCCAGGGGATCCAGGGAAGTGTCGTTGAGGCCTGTGGCTCTGTGGGGTCGTTCAGGGGGAGGTGCGGTGAAGTCCACATTGTCCATGGAGTTGTTTGGGGGCCCTTCTTCCCCGCAGTGGGGCTGCCCTCTGCTGGTCACTCTGGGGGACCCCTGCCTCCATTTTTCCCTTCCCCACACACCCCACTGGGTTTGGAGTGAAAAAGGAGTGAATGAAAAAGGAGGGCGCTCTACACCCTTTCTTTTGTCTTAGAGTGACTGCTCCTCCCACAACCCCAAGATGGGAGAGGGAGATGGTGAGAAGAGAAGAACCAGGAGAGGGAACCAGCCGATCATCCCCACCCACCTGCCCCAGAGGGTGCAGCTCAGGCCTCTGCCTGTCCTGGGCAGCCTGCACCGCTGCTCTGCTCAGCTCCTTGGATTGAGGAGATCCCTATTCTGCCCTAGGTGGAGCCCCACAATAGGTCTCTCTGAAGTCTTTTCCCCTCTCTGGACCTAAGTGTCTTAATCTCTCTTAAACAGGAGGTTGCAACACTGGCCTCCCTGATTCCACCTTCAACAGGATGGGACTCTATGGCTTCGAATGTAACCCACATCAGTCTTGCTCCTAAAGAATCTGCCCTTCCACAAATCACCAACCCCTATCCCGCCCCATGTCACCCCCTGTGCTCCTTCCCAG
Seq C2 exon
GTGCTGACCTGACAGCAGTGGACCCTGTTCGGGGCAAGACGGCCCTGGAATGGGCAGTGCTGACCGACAGCTTCGACACCGTGTGGAGGATTCGGCAGCTGCTGAGGCGGCCCCAAGTGGAGCAGCTTAGCCAGCACTACAAGCCCGAGTGGCCGGCCTTGTCCGGGCTCGTGGCCCAGGCCCAGGCCCAGGCCCAGGTTGCCCCTTCACTCCTAGAACGGCTGCAGGCTACCTTGAGCCTCCCCTTTGCCCCGTCTCCTCAGGAGGGGGGTGTTCTGGACCACCTTGTGACTGCCACAACCAGCCTGGCCAGTCCCTTCGTCACCACTGCCTGCCACACTCTGTGCCCTGACCATCCACCTTCGCTGGGCACCCGAAGCAAGTCCGTGCCAGAGCTGTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167612-ANKRD33:NM_001130015:4
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.287
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(33.9=43.8),PF127962=Ank_2=PU(44.7=70.8)
A:
NA
C2:
PF127962=Ank_2=PD(53.9=30.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCTCTAGTGAGTCTCCTGC
R:
AGCCGTTCTAGGAGTGAAGGG
Band lengths:
358-1429
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)