HsaINT0019253 @ hg19
Intron Retention
Gene
ENSG00000154473 | BUB3
Description
budding uninhibited by benzimidazoles 3 homolog (yeast) [Source:HGNC Symbol;Acc:1151]
Coordinates
chr10:124922128-124924886:+
Coord C1 exon
chr10:124922128-124922344
Coord A exon
chr10:124922345-124923335
Coord C2 exon
chr10:124923336-124924886
Length
991 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
TTTTTCTTTTGAACTTGTAGGTC
3' ss Score
10.31
Exon sequences
Seq C1 exon
GTGGTTCTGATGGCTTTGTAAATATTTGGGATCCATTTAACAAAAAGCGACTGTGCCAATTCCATCGGTACCCCACGAGCATCGCATCACTTGCCTTCAGTAATGATGGGACTACGCTTGCAATAGCGTCATCATATATGTATGAAATGGATGACACAGAACATCCTGAAGATGGTATCTTCATTCGCCAAGTGACAGATGCAGAAACAAAACCCAA
Seq A exon
GTGAGTATGCTTCACCTGTATTTGAGCCTTTTCTTGCATTCAACCCAGGATTTATTAATTTTTCTAAATTCATGAATAGCATTGTTGATGCCTGCTCGATATTACAGCTGACTGTAGGGTTGGAGTTGATGTTATCATGTTCTCCCAAGCTTTCAATATCCGTAGGTTGATAGACGTCTGATGGATAAAATTGTGCCTAGTTGTTTTGTAGAGAAGAATGTCAAACTCTTATTCTTCTTGAATAGGCTCTATTATTTGAATCTCTGGAGTTATTACCAGCTCATTGCTTCAAAATTAAGTTGAGGAATTCAAGAATAATTTATTTTAGTAAATTCTATTTAAGATGTTTAAGAATTTGAACTGCCAAAAATCTTTCCTCTCCACAGAGGTTGTTTCTTTAATATTAACACAAAGTAAGTGACCTTCAGGTCTTATTGGAAACTCAGAGTAATATGGCCTTGCCTGGAATTGCAAATTTCCTTAGTTTTGAAATTTTCATAGATGTCTTTGGTTCTTGGTTGTAACTGTTGACTGAGAAGAGCCATTTACATTTTTTGATACCAACAGGGCAAAGCTTTTTACTTAATTACCTCTACCAGGCTTTAAGGGAAATCTGATACTTCAGCATGTGTTAAACTATAAAATACCTACTCCAAGTATCTGCCCAGTTCCTTGTCCCCTCTCCCCAGGCCCTTAAAGGAAGTTCTCGATACATATTTGTAGAATAACTGAATGTTTTCAGGATTCCTGTACTTTGCTGAGTTAAAATGGATATGGTACCCTTGCTGATTGGTTGAGCCCCTAAGAGGGGGCAGAATATTAAATATTCCATATCAGATATGCTTTTACAGGTTTGACTTTAGAAAAGTCTTAGCATGTGAAGCCTGTTGGATAAAGGGCTGTGTTTGCATTTAATCTGTCACTTTTGTATCTCCTGTCCTGGCTGGCCATTTTGATCTCATGCTGTTCTTTTTTTCTTTTGAACTTGTAG
Seq C2 exon
GTCACCATGTACTTGACAAGATTTCATTTACTTAAGTGCCATGTTGATGATAATAAAACAATTCGTACTCCCCAATGGTGGATTTATTACTATTAAAGAAACCAGGGAAAATATTAATTTTAATATTATAACAACCTGAAAATAATGGAAAAGAGGTTTTTGAATTTTTTTTTTTAAATAAACACCTTCTTAAGTGCATGAGATGGTTTGATGGTTTGCTGCATTAAAGGTATTTGGGCAAACAAAATTGGAGGGCAAGTGACTGCAGTTTTGAGAATCAGTTTTGACCTTGATGATTTTTTGTTTCCACTGTGGAAATAAATGTTTGTAAATAAGTGTAATAAAAATCCCTTTGCATTCTTTCTGGACCTTAAATGGTAGAGGAAAAGGCTCGTGAGCCATTTGTTTCTTTTGCTGGTTATAGTTGCTAATTCTAAAGCTGCTTCAGACTGCTTCATGAGGAGGTTAATCTACAATTAAACAATATTTCCTCTTGGCCGTCCATTATTTTCTGAAGCAGATGGTTCATCATTTCCTGGGCTGTTAAACAAAGCGAGGTTAAGGTTAGACTCTTGGGAATCAGCTAGTTTTCAATCTTATTAGGGTGCAGAAGGAAAACTAATAAGAAAACCTCCTAATATCATTTTGTGACTGTAAACAATTATTTATTAGCAAACAATTGATCCCAGAAGGGCAAATTGTTTGAGTCAGTAATGAGCTGAGAAAAGACAGAGCATATCTGTGTATTTGGAAAAATAATTGTAACGTAATTGCAGTGCATTTAGACAGGCATCTATTTGGACCTGTTTCTATCTCTAAATGAATTTTTGGAAACATTAATGAGGTTTACATATTTCTCTGACATTTATATAGTTCTTATGTCCATTTCAGTTGACCAGCCGCTGGTGATTAAAGTTAAAAAGAAAAAAATTATAGTGAGAATGAGATTCATTTCAATGTAATGCACTAAAGCAGAACACGAACTTAGCTTGGCCTATTCTAGGTAGTTCCAAATAGTATTTTTGTTGTCAAACTTTAAAATTTATATTAATTTGCAAATGTATGTCTCTGAGTAGGACTTGGACCTTTCCTGAGATTTATTTTATCCGTGATGTATTTTTTTTAATTCTTTTGATACAGAGAAGGGTCTTTTTTTTTTTAAGTATTTCAGTGAAAACTTGGTGTAAGTCTGAACCCATCTTTTGAAATGTATTTTCTTCATTGCAGGTCCACCTAATCATCCTGTGAAAGTGGTTTCTCTATGGAAAGCTTTGTTTGCTTCCTACAAATACATGCTTATTCCTTAAGGGATGTGTTAGAGTTACTGTGGATTTCTCTGTTTTCTGTCTTACAAGAAACTTGTCTATGTACCTTAATACTTTGTTTAGGATGAGGAGTCTTTGTGTCCCTGTACAGTAGTCTGACGTATTTCCCCTTCTGTCCCCTAGTAAGCCCAGTTGCTGTATCTGAACAGTTTGAGCTCTTTTTGTAATATACTCTAAACCTGTTATTTCTGTGCTAATAAACGAGATGCAGAACCCTTGAATGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000154473-BUB3:NM_004725:7
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.129 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(32.3=13.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGACTACGCTTGCAATAGC
R:
GCCCAAATACCTTTAATGCAGCA
Band lengths:
350-1341
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)