HsaINT0108343 @ hg19
Intron Retention
Gene
ENSG00000041515 | MYO16
Description
myosin XVI [Source:HGNC Symbol;Acc:29822]
Coordinates
chr13:109777460-109779898:+
Coord C1 exon
chr13:109777460-109777706
Coord A exon
chr13:109777707-109779629
Coord C2 exon
chr13:109779630-109779898
Length
1923 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
3' ss Seq
GTGTTTTGTTTCCCCCTAAGAAC
3' ss Score
6.32
Exon sequences
Seq C1 exon
TTATCAGAGGATTTTTAGCACGCCAGCACCTGCTTCAGAGAATAAGCATCAGACAACAAGAGGTGACTTCTATCAATAGCTTTCTGCAGAACACAGAGGACATGGGGCTGAAAACCTACGATGCCCTGGTCATTCAGAATGCTTCAGACATTGCCCGGGAAAATGACCGGCTCCGTAGTGAAATGAACGCTCCCTACCATAAAGAGAAGTTAGAGGTCAGGAACATGCAAGAGGAAGGAAGCAAAAG
Seq A exon
GTAAAGGCAGAGAGCATGCAATTTTAATTACCTTTGTGATTGGTTCAGTGGAGTCATGAAAATTCAAATAGCCCTTAATGCAGAGTTCAATCAAATATGACAGGAGTTGCAGGAACAGGCATGCGTGGTTTGTTATTCGAAATGGCAGCAGTCTAAAAAGATGCTTTCCTGTGCTGTCTTCTCACGAGTTCAAGGCTTTCTGTGTTCCTTCATTCATATGTGATGATGACTGCCTCTCCTGCCATGCTTGTGTCACTTAACTACCTCAAGCACACTCTAGTTCTAAAGCATTTACTGTTTCTGTATTAGCAAAAATATATAGCTTGGCTGTTGACATTTTTACACAAGCGTTACGGATATAAGGCTGGCTTATAGAAACTTCTGGAAATCTGACCCAAAAAATGGAGATACCACTCTGAAAACATGGAAGAAGTGAACTCAATAGATAGATTGTAAGTGTATTATATATCCCTGTGTAAACTGTCACGTCTCTCTTTACCAATAAAGCAAGCTTTGGGGAAAGCTTTGTATTTAAAAGTTCACTTTAGAGGCTTAGCTTAAAACAGAAATGTGACGATCACCTGGTCCCTCTCCATTTGATCACTCTCCTCTCTCTGTGAATGATGAAGACACCCGTGAATCACAACACCCCTAAGAGGGAGGGCAAGGAGCTGCTTCCTTTGGACCTTAATTCATCGTCAGGGAGATGTTTGTTTTGCTATAGAAACTTGGTAATATCTTGTTGTTTCTCACTGAAAATGACTCTCCTTTCCCATTTCTGCCGATGTCAATTTTTTTTTATTAAAGTGGAAATGGCAATGTGTATCTTGTTAATTAGCTTCAAATATCTCAGTGATTAAATACTGAAAAAAATCCCCTTTGTACAGAAAAAAAGACTGTAATTAAACATTACAGGAAAAACAAATTATCCACTGAGTGCCATGCTTTCATCTTCAGCTATTTCATTTTCTACATGGGCGGCTGGCTCTGCCTTGTGGTAGATTCTAGCCCTGTTGGTGTTCTGCCACAGAAAGATATAATTATAAAAACAAACGCTTGGAAACTCCTTGTAGAATGAATGCATTGGCATCTTGCTAGCACATGATTACGTTGACATGCGAAGCCAGAAGAAGTTTTTTTAAGCAAGATAACTATTAATTTTATATGACTTCCAAAATAATATTTATTATTTTCTCTGCTGGAACTAAACGGCCACCCCAATTTCTCAATTTGATTATGTATGTATTTTCCTGATACAAAATTAAGTGAAGAAGTATTTGTCTGTTTATTTACTGAATACCAGCAGTTTACTTGGCACTGGACAACCATATGGAGTCAAGGAGGAGAAATAATAGCTCTGCACATAATTAAATAATTTCTGGTAGAATTTAAGAGGCAAGAAAGAGAGTAATGGGGAGAAGGAGAACACTGAAATGTAAATTTCTGAGAGTTTTAAGTAGAGTCTATCCTCTTGCGAGGGGAAATGGTGATGAACTCCCAGCATTTGATGCATCAGTAACTCTCTATTAAGATGGATTTGCCAGAAATTATCATTCAGATTGAAATTCTGGTTTTTTGATTTGCTTAATAATCAGAGTGTGAAGAATTCATTCAGTGAGTGCCTGATGGAAAATGCGAAGGCCCTTAAGTAGTGTTGCGTTTGTGTGAGAATGTTTAAAAAGTAATCATGATGGATATCCCGCGGGCTCATGTGCTTTTCATCACAAAGCCGGAGCCAGAGGACGGGTGGCCTTCTCTGGACCAACTGGTCACCAGAGGGCTGCACACGTCCTCCAGCCACAGCAGGAAGGGCTGCTTGCCAAAAAGCCGTCATTATGTCTGCTTGAGCAGGTTCCTTGTTACCGGAATAATGCATCTGGGCCTCTCTGGCGTGGTGCTGTTTGTGTTTTGTTTCCCCCTAAG
Seq C2 exon
AACCGATGACAAGAGTGGACCCAGGCATTTCCACCCCAGCTCCATGTCAGTCTGCGCGGCCGTGGATGGCCTGGGCCAGTGCCTCGTTGGCCCGTCCATCTGGTCTCCTTCGCTGCACTCGGTGTTCAGCATGGATGACAGCAGCAGCCTCCCGTCTCCACGGAAACAGCCCCCGCCCAAGCCAAAGAGGGACCCCAACACCCGGCTGAGTGCTTCCTATGAGGCTGTGAGCGCCTGCCTCTCCGCGGCCAGGGAAGCGGCCAACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000041515-MYO16:NM_015011:30
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.349 A=NA C2=0.659
Domain overlap (PFAM):
C1:
PF0061222=IQ=PD(52.4=13.3),PF154391=NYAP_N=PU(23.3=37.3)
A:
NA
C2:
PF154391=NYAP_N=PD(75.9=93.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCTGGTCATTCAGAATGC
R:
GCCTCATAGGAAGCACTCAGC
Band lengths:
351-2274
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)