HsaINT0111709 @ hg19
Intron Retention
Gene
ENSG00000166579 | NDEL1
Description
nudE nuclear distribution E homolog (A. nidulans)-like 1 [Source:HGNC Symbol;Acc:17620]
Coordinates
chr17:8366638-8371481:+
Coord C1 exon
chr17:8366638-8366672
Coord A exon
chr17:8366673-8370247
Coord C2 exon
chr17:8370248-8371481
Length
3575 bp
Sequences
Splice sites
5' ss Seq
TGGGTAACT
5' ss Score
4.34
3' ss Seq
TGCTCTGGTTGCTCCCACAGGGC
3' ss Score
10.2
Exon sequences
Seq C1 exon
GCAAGAAAAAGTCATATTTCCCACGTTGTTCATGG
Seq A exon
GTAACTGAATTTGTTTGCTGTGCTCTTTTTCATTCTTTCTTAATCCTGGTGTGTGGTGGAAGACACATTAACAATCTGGTTTTACTAACTGCATGGGGCTGACTCAGCTTTAACCAACTTACAGCCCATCAGTGAACTTTCACGGTCCTGTTCGACTTGACTGTATGCCGTTATTAGTTCAGCTGTGAGAAACAAGAACAAATTAGTTGCAGTGGTCCTGGGGTGGCTGGGAGTAGCATGCCAGGTGGCACGCCTGAGATGGGCTAGGGCGCTGTAGTGTTGATTTCAGAGTCTGGCGATGGGGGTTTGAGGTCACTGTCAGGCCCTGGGATCACCTTTGACTGTCTTCCTGGGACTGGGGGTCTTCCCGTTACCCAGTTGCTTCTGTTTTCTCAAGTCAGGCACCAGTGTGAGCATTCCCTCACCTCTGCGCTCACGCATGGAGTCCCCAGTTAAAATGGAATGGTACATGGGGACGTGTGTAAGATCTGCCTTACATTTCAGAACTGCTTTGCAGTTTGCAGAGCCTGGGCTGAGAACTGGAGCAGGCTGGAGCTGCTCTGAGCCCACACTCATCCACTGAAATAGGAGACTCAGGTGTGGCGTGTGCCTGCCTGCAGGCTCTTCTGGATAGCTTGAGCCCACCCTCCTGCCCTCTCCAGTGTCCTGATCCTTGCTGCTTTGACAGAGTTAATGTTTCCATCCTTCATCTCAGCTGCTTTGGATTTATTGTCCTGAGTAGCTTCTAAGTGTGCCTTGGCTCTTCCCCCTTTTCACTTCTTCCACTGACATTTTACAACTGACCTTAGCACTTTTTCTTAGCTGGATTCTCTATATTTCAGCCTCCTTAACTAGTCTGTGGTGGTAAGATCATGAAATTTTATAGCTCTGGAACCTTTTTTTTACATATATGATTCCCAGATCTGTATCTTCAAGCCTGCCCCATCACTCTTCCTTCAGTCCTGTCTTGTGCACTGGGACATTGCCCTGTGGCTCTTTGCTGCTCCCTGAAACTGAATCTGTTGAATATAGAGTCTCTTCTCTTGCAAATCTTTTCCCCATGCACAGCTTTGCAGGCCTCTGAAGGACTTCACTAGACCTGTCATCCCATCTAGAAGGCCAGCTTTCTTCTCTCTCTGTTCTTTAACTTTCTACTTTTTGAGTCAGGAGAGAGGCGCTAGGTGAGACCCTGGTGGATTGATGTTCCCTCTCTACTCCACCCACCTTCACATTAAGCGTTCCATTTCTGCCCATGTAGAAATTTACCGGTTCTCTCTTTATAGTCTGGGCTGCACCACTTACTTTTCCCATTAGAGCCGGCCTGCATTGGAGTGCCGAAGTGGTTGCTTCTGAGGGCTGCTAGGTGGCCTCTGACCAGGAGGAGACTAGAAAAGGGTCCTGGCCTGGGCATCTGGAGGCAGCTGTGGCCCCGACTTCCCCATCAGTGGCTCACTAGGTGAGCCTAGGCTAATGGCTGGACCTTCTCTTGCTTTGGTTGTCTTGGCAGTGGAACAGTGGGATGAACCTGTTGTTCCTTACGGTGCACTTGAAAATGCCAGAATCCCATCCTCAACCTGCTTGAGGAGCCATCTCCTAGTTGCTGCTTTTGTACACCCCCGTGGCCCAGGTGCCAGATTCTTCTTGGCATCCAATGGTGCTCCCTTTCTGCTGGGTTCCGGGCACTGTCTGCAGTACAGGTTTAGGGGCTTGCCTGCCACTGTGATGTGTGAGGCCAGGAATCTGAGGTTCACACGTGCTGAGAGCTGCAGGCATTTGTGGGGCCTGCCTGGTTGTCCCTGAGGTTTCTAGGAGAAGCAGGTGTCAGGGACTCTGGGACTAGCCAGACAGATGGAGCCTATTATATGAGGGCTACCGTGGCAAATAGGATATGGCCTTGGCCCCAGAAGAGGCACAGGCCTGTGACCTTGGGAGAGTGGGAAGGATGATTTCAAACTTGCAAATGTGTTGAAGCTCAAAAATCAGACCTAACCCAGTGAGGAAAGAGACAATCTGGCTGTTTGTCGTCGAAGTAGGACAGTGTGCAACAGGGAGAAATGACATTTGTCAGAGCCTTTCTCCTGGGGCTCTTGGTCTCTGTATGCGTGGTTGGAATTTAAACTCCACATATGTACTCTGAGTTTAGTTTCTTTAGACATGAACTTTGTTTCTTCCAAGTAGGCAGGGACTATTTGTCAAGTCTCTGCATGCCTGTTTGTCTGTGAGGTTATCCTCACCCCGTCAGTGTACGAAACAGCTGTCTCTGCAGGGAGTGTGTGTCGGCATTTTTTTTTTTTAAGGAGAACCTCTCTCCATGAGTCTGTATTTAGCTCCCTGGAGCCGTCTGATGAGTAGGTGGGGGCAGTAGTGGGCAGGTGTGGTGCAGTGTGGCCCCTTGTCGTAGTTGGCTTTATCTCCCAAATTGCTAGTGGGACAAATTTTCCTAGGAAGCGTTTCAAGGTGGAAAGGCTGAAGTGGCTCCTGAGAGAGGTTCCAGGCTGCACACTCCCTCCCCCTCTTGCTGCTTCCTGTGGCTGCGCTGCATGGTGCGTGAGGGGGATGCTTGGGGGGCTCCCTGCATCGCTGGGCTCTGGGTGCGTGATGGGGACGCTGGGGGGCTCCCTGTGTCGCTGGGCTCCGGGTGCTGGGTCCTGGCTGCAGGCTATTGGGTTGGGCTGGGCTGTCTGCACACGAGTCTGCGTTGAAAAGCCTACTCATCTGGCGTTGCTTGCTAAACAATTTTTAAAAGGTTATTTTTCTCCACCTTATTAAGATATTCGTGTATTAATACATTATATTTGGAAAATGTAAGGAGATTTGGAAAATGATTAAAAAAGGATAAAGTAGTAAACAAAATTCACCCACAGCCCAGAGGGAAGAAAAGTAACGATTCTTAAATTTTCTTTTTATGATATATATGATCCTATGTACATATATGTTGGTGTGTGTATATATATATGTGTATGCGTATATATAATGTATGTATATATACATTTATTTATACACACTCCCCCTCTGTCCCTGCTTTGTGGATTTAGCTGCATGGATAGTAATGTCTATCTAAGGGGCTATAGTCTAGAATCTAGAATATATACTATTTGCTTTTTTTTCTTTCATATCATTGAATCTACAGAGTTTGGTAACCTGCATCTTTTTCCACTTAGTGTTAGTTACATTCTGAATATTTTCCCATGCTATTAAAAAACTTGTGGAATGTGTTTTTAATGGCTGTGCAATATCTTATTGTTCAGTTGTACCATTATTTATTTAACTAGTTCCCTATTGCCAGGCATTTAGACCTGCTTTATGGGGAAAGAATCAGGACTGTGGCTTCCGTGGCCAGTGTGCGGCAGTTGCCAAACAGGTCATGTGGTCCTGGTTCCCCAGGATTCCCAAAGGCTCAATTCTCTAACCAGCTGGTGCTTTCCAGGCAGCCAGTGCCCCTTGGGCCATCAGGACCCTACAGCCTGCGAGGAATAGTTTTAGAAAGCAGATTAATTTCCTATTGTGTGTGAGTGATTTTAAATGAGTTTTTCGTTTCCCCTTTCTTCCCTTCTGTGCTCTGGTTGCTCCCACAG
Seq C2 exon
GGCAGTAAACGGCTTTGACCCCGCTCCTCCTCCTCCTGGTCTGGGCTCCTCGCGTCCATCGTCAGCGCCGGGTATGCTGCCTCTCAGTGTGTGAGTGCCTAGCCTCCAGGTGGGGGCTCCTGCCCTCCTCCAACAACCCAGGACACCCACGCCTCACCCCTCGGTGCCTGGGCCCAGCCCCGTGCCCCTCCGTCTGCCTCCGCACGGCTGGCAGAGGGCAGGCTGCATGCAGTGGCGGCTACTGGGCCCTGCCCAGCCCCGGAACTCTGCGCGATATCAATACTGGCTATTTTCTCTTCTCGCCGTAGTGCCGTTGGTTTCACATGATTGCACTTTTGTGGGTCGCAAGGTGATACATACGTGTATTACTTGGTCACTGGATGCAGAAGTACCCATTCATCACACCTGCCCCATAGCCCCCACTCTGCTGTACTGATAGGATTTAGTTGTGTTTTAGGACATTGCAAATCTTCTAGAAGTTCTCCCCCAAATCAGGTCAATGTGTGCCCTCCTGAGCTCCCACCCAGGCATCTCCAGTGCTCATGATCATGTGTCCCCCAACTCCACCCCTCACAGTTTGGGCCTGTTTCTGGCAAAGAGTCAGGAAGGTTACTGAATTAGGGAACATTTTCTGCACCTTCTGATTTTACTTAAGCAGCTACCATTCCATGGACTTGCCTCCCAGAGCAGCACAATGCCCGTCTGAGCCCCACGTGGCAGGAGCCTCTGGGACGGGGCACACACAGGCCCAGCCTCTGTGCTGTCTCCTCCTCCGTGCGCCTCAGACTCGGGGTGAGGGAGGCGGGCAGCCTCTCGCCAGCCTTCCCGTCCTTCAGTTCAACGACATCTTTGGAGTGTTTTTGTTTTCTCTTCCAAGGGCCGTCCCGTTGTGTTAGGAAGGGTGAGTGGCTGGTTCCAGGGTGGGCCGGTGCCAGCTCCGGGGTGGACTGAACAGCGGCGGCTGTCCCTGTGCATCCTTTGATTACTCTCATGCTGCATTTACTGTTTACATTTGTTTTATTGTACATAGGTTTGTAAACATTATTGCCTGAGATATTTGTATATAACTTGGGCTTTGTAGCTTTTATTTATTCAGAACGCATACGGCATGTTAATGACTCTGATGGTGTCCTCCTCTGGGCAGCTGTATAGGATCATCATGTGGTTACAAAAAATACTTCCCTCAAAAAAATTCTTTTAATGTGGAAACAATAAATTTCACAGAAAAAAAGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166579-NDEL1:NM_001025579:9
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.906
Domain overlap (PFAM):
C1:
PF048808=NUDE_C=PD(5.2=76.9)
A:
NA
C2:
PF048808=NUDE_C=PD(10.4=65.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)