Special

MmuEX0003021 @ mm9

Exon Skipping

Gene
ENSMUSG00000041828 | Abca8a
Description
ATP-binding cassette, sub-family A (ABC1), member 8a [Source:MGI Symbol;Acc:MGI:2386846]
Coordinates
chr11:109926479-109930182:-
Coord C1 exon
chr11:109930092-109930182
Coord A exon
chr11:109929339-109929478
Coord C2 exon
chr11:109926479-109926598
Length
140 bp
Sequences
Splice sites
3' ss Seq
TTTTAATTCTTGAATAACAGCTT
3' ss Score
4.24
5' ss Seq
CAGGTAATT
5' ss Score
8.55
Exon sequences
Seq C1 exon
ATAGGAAAGTGTTCATCTCCAAGGGGAAGCTGAAGTGTGCAGGATCTTCTTTGTTTCTGAAGAAGAAATGGGGGATTGGTTATCACTTAAG
Seq A exon
CTTGCAGCTGAGTGAAACGTGTGTGCATGAAAGAATAACATCACTTGTCAAACAGCACATCCCCGATTCCAAGTTGTCAGCAGAAAGCGAAGGGAAACTGAGCTACATATTACCCCTGGAAAGAACAAACAAGTTTCCAG
Seq C2 exon
ATCTTTATAGGGATCTCGAGAGAAGTCCAGACCTGGGAATTGAGAACTATGGCGTTTCTATAACAACACTGACTGAGGTCTTTCTGAAACTGGAAGGAAAATCATCTATTGACCAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041828-'20-22,'20-20,21-22
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000097860





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000045808, ENSMUSP00000102275
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:69191176-69191315 
ALTERNATIVE
HsaEX0000242
(ABCA10)
Human
(hg19)
chr17:67187317-67187456 
ALTERNATIVE
HsaEX0000242
(ABCA10)
Rat
(rn6)
chr10:98363466-98363605 
HIGH PSI
RnoEX0004967
(Abca8a)
Cow
(bosTau6)
chr19:62123081-62123220 
HIGH PSI
BtaEX0001734
(ABCA9)
Chicken
(galGal4)
chr18:8217780-8217919 
HIGH PSI
GgaEX7009488
([1])
Chicken
(galGal3)
chr18:7953271-7953410 
Zebrafish
(danRer10)
chr12:38662175-38662314 
HIGH PSI
DreEX0009949
(abca5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TAGGAAAGTGTTCATCTCCAAGGG

				
R: 
CTGATTGGTCAATAGATGATTTTCCT

				
Band lengths: 
210-350

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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