Special

MmuEX6006006 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108399250-108406218:+
Coord C1 exon
chr6:108399250-108399375
Coord A exon
chr6:108401313-108401513
Coord C2 exon
chr6:108406090-108406218
Length
201 bp
Sequences
Splice sites
3' ss Seq
CACTCCTTGTCTTGTGCCAGATC
3' ss Score
8
5' ss Seq
GAGGTGACA
5' ss Score
3.85
Exon sequences
Seq C1 exon
GCCGAAGACACAAAGATGCAAGAGATCATGCGGCTGGCTCATGAATTTTTGCAGAATTTCTGTGCAGGCAACCAGCAGAATCAAGCTTTGCTGCATAAACACATAAACCTGTTTCTCAACCCAGGG
Seq A exon
ATCCTGGAGGCAGTGACGATGCAGCACATCTTCATGAACAACTTCCAGCTGTGCAGTGAGATCAACGAGAGAGTGGTCCAGCACTTTGTTCACTGCATAGAGACCCACGGTCGAAACGTCCAGTATATCAAGTTTCTCCAGACGATTGTCAAGGCAGAAGGGAAATTCATTAAAAAGTGCCAAGACATGGTCATGGCTGAG
Seq C2 exon
GCCTGTAACAACACAAGCGACAGGAAGCACGCAGACTCCATTCTGGAGAAGTACGTCACTGAAATCGTGATGAGCATCGTCACCACCTTCTTCAGCTCTCCCTTCTCAGACCAGAGCACCACTCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102_MULTIEX1-30/59=29-33
Average complexity
C3
Mappability confidence:
96%=97=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0136516=RYDR_ITPR=FE(22.8=100)

							
A:
PF0136516=RYDR_ITPR=FE(36.7=100)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032192





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000144880
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4691144-4691344 
ALTERNATIVE
HsaEX0032551
(ITPR1)
Human
(hg19)
chr3:4732828-4733028 
HIGH PSI
HsaEX0032551
(ITPR1)
Rat
(rn6)
chr4:140434443-140434643 
HIGH PSI
RnoEX6014530
(Itpr1)
Cow
(bosTau6)
chr22:21769944-21770144 
HIGH PSI
BtaEX6093954
(ITPR1)
Chicken
(galGal4)
chr12:18453283-18453483 
HIGH PSI
GgaEX1030871
(ITPR1)
Chicken
(galGal3)
chr12:19096919-19097119 
HIGH PSI
GgaEX1030871
(Q9DEX2_CHICK)
Zebrafish
(danRer10)
chr11:35661675-35661875 
HIGH PSI
DreEX6092756
(itpr1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCCGAAGACACAAAGATGCAA

				
R: 
TGCTCTGGTCTGAGAAGGGAG

				
Band lengths: 
244-445

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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