MmuEX6056586 @ mm9
Exon Skipping
Gene
ENSMUSG00000023033 | Scn8a
Description
sodium channel, voltage-gated, type VIII, alpha [Source:MGI Symbol;Acc:MGI:103169]
Coordinates
chr15:100814120-100838722:+
Coord C1 exon
chr15:100814120-100814476
Coord A exon
chr15:100832465-100832597
Coord C2 exon
chr15:100838484-100838722
Length
133 bp
Sequences
Splice sites
3' ss Seq
TGCTTTATTTTATTTCTCAGGCA
3' ss Score
9.26
5' ss Seq
AAGGTGTGT
5' ss Score
6.64
Exon sequences
Seq C1 exon
TCGCTGCTCAGCATCCCAGGCTCGCCCTTCCTTTCCCGACACAACAGCAAAAGCAGCATCTTCAGCTTTCGGGGTCCTGGACGGTTCCGGGACCCCGGTTCGGAGAACGAGTTCGCAGACGACGAGCACAGCACAGTGGAGGAAAGTGAGGGCCGGCGCGACTCGCTCTTCATCCCGATCCGCGCCCGCGAGCGCCGCAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGTGCAGCCGCTCGTCGCGCATCTTCCCCAGCCTGCGGCGCAGCGTGAAACGCAACAGCACCGTGGACTGCAATGGCGTGGTGTCGCTCATCGGGCCTGGCTCGCACATCGGGCGGCTCCTGCCTGAG
Seq A exon
GCAACAACTGAGGTGGAGATTAAGAAGAAAGGCCCTGGATCGCTCTTAGTCTCCATGGAACAACTCGCCTCCTACGGACGGAAGGACAGAATCAACAGTATAATGAGCGTTGTCACAAACACACTAGTGGAAG
Seq C2 exon
AGCTGGAAGAGTCTCAGAGAAAGTGCCCACCATGCTGGTATAAGTTTGCCAATACTTTCCTCATCTGGGAGTGTCACCCCTACTGGATAAAACTGAAGGAGATTGTGAACCTGATCGTCATGGACCCTTTCGTAGACTTAGCCATAACCATCTGCATTGTCCTGAACACACTATTTATGGCAATGGAGCACCATCCCATGACGCCACAATTCGAACATGTCCTGGCCGTAGGGAACCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023033-'12-13,'12-11,14-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.302 A=0.016 C2=0.000
Domain overlap (PFAM):
C1:
PF0310514=SPX=PD(27.7=44.5),PF119333=DUF3451=FE(52.0=100)
A:
PF119333=DUF3451=PD(16.5=86.7)
C2:
PF0052026=Ion_trans=PU(1.6=3.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACAGTGGAGGAAAGTGAGG
R:
GGTGGGCACTTTCTCTGAGAC
Band lengths:
258-391
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: