MmuEX6073798 @ mm9
Exon Skipping
Gene
ENSMUSG00000028125 | Abca4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424]
Coordinates
chr3:121850349-121851970:+
Coord C1 exon
chr3:121850349-121850423
Coord A exon
chr3:121850648-121850817
Coord C2 exon
chr3:121851793-121851970
Length
170 bp
Sequences
Splice sites
3' ss Seq
AACCTGTCTCTGCCCTCTAGGTA
3' ss Score
10.56
5' ss Seq
AGTGTGAGC
5' ss Score
3.73
Exon sequences
Seq C1 exon
GGTCCTGTCACCAGGGAGGCCTCCAAAGAAATGTTAGATTTCCTCAAACATCTTGAAACCACAGACAACATTAAG
Seq A exon
GTATGGTTTAACAACAAGGGCTGGCATGCCCTGGTCAGCTTTCTGAATGTGGCTCACAACGCCATCTTACGGGCCAGCCTGCCCAGGGACAGGGACCCTGAGGAGTATGGAATCACTGTCATCAGCCAGCCTCTGAACCTGACCAAGGAGCAGCTCTCGGACATCACAGT
Seq C2 exon
ACTGACTACTTCCGTGGATGCCGTGGTTGCCATATGTGTGATTTTCGCCATGTCCTTCGTTCCAGCCAGCTTTGTCCTTTACTTGATCCAGGAGAGGGTGACGAAAGCTAAACATTTGCAGTTTATCAGTGGTGTGAGCCCCACCACCTACTGGCTGACCAACTTCCTCTGGGATATT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028125-'45-46,'45-45,46-46=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.080 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=PU(6.7=80.0)
A:
PF126982=ABC2_membrane_3=FE(18.7=100)
C2:
PF126982=ABC2_membrane_3=FE(19.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTCACCAGGGAGGCCTC
R:
CAGAGGAAGTTGGTCAGCCAG
Band lengths:
242-412
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000568; ELM sequence: LNLTKE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: