BtaEX6016499 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000018010 | ABCA4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:HGNC Symbol;Acc:HGNC:34]
Coordinates
chr3:49655927-49658511:+
Coord C1 exon
chr3:49655927-49656001
Coord A exon
chr3:49656251-49656420
Coord C2 exon
chr3:49658334-49658511
Length
170 bp
Sequences
Splice sites
3' ss Seq
GCCACCTTCCTGTCCTCTAGGTG
3' ss Score
11.59
5' ss Seq
AGTGTAAGC
5' ss Score
5.32
Exon sequences
Seq C1 exon
GGCCCTATGACCAGAGAGGCTGCTAAAGAAATGCCTGCTTTCCTTAAACAACTAGAAACTGAAGACAATATTAAG
Seq A exon
GTGTGGTTTAACAACAAAGGTTGGCATGCTCTGGTCAGCTTCCTCAACGTGGCCCACAACGCCATCTTACGGGCTAGCCTGCACAAGGACAAGAACCCCGAGGAGTATGGCATCACCGTCATAAGCCAGCCCTTGAACCTGACCAAGGAGCAGCTCTCTGAGATCACAGT
Seq C2 exon
ACTGACCACTTCGGTGGACGCTGTAGTGGCCATCTGCGTGATTTTTGCCATGTCCTTCGTCCCTGCCAGCTTTGTCCTTTATTTGATCCAGGAGAGGGTGAACAAGGCCAAGCACCTCCAGTTTGTCAGCGGAGTGAGCCCCACCACCTACTGGCTGACCAACTTCCTCTGGGACATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000018010-'42-35,'42-34,43-35=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.040 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(7.3=100)
A:
PF126982=ABC2_membrane_3=FE(17.1=100)
C2:
PF126982=ABC2_membrane_3=FE(18.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTATGACCAGAGAGGCTGCT
R:
AGAGGAAGTTGGTCAGCCAGT
Band lengths:
242-412
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000568; ELM sequence: LNLTKE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]