RnoEX6011357 @ rn6
Exon Skipping
Gene
ENSRNOG00000012892 | Abca4
Description
ATP binding cassette subfamily A member 4 [Source:RGD Symbol;Acc:1309445]
Coordinates
chr2:225751930-225753594:+
Coord C1 exon
chr2:225751930-225752004
Coord A exon
chr2:225752233-225752402
Coord C2 exon
chr2:225753417-225753594
Length
170 bp
Sequences
Splice sites
3' ss Seq
AACCTGTCTCTGCCCGCCAGGTG
3' ss Score
9.98
5' ss Seq
AGTGTGAGC
5' ss Score
3.73
Exon sequences
Seq C1 exon
GGTCCTGTCACCAGAGAGTCTTCCAGAGAGATGTTAGATTTCCTCAAACACCTCGAAACCAAAGACAACATTAAG
Seq A exon
GTGTGGTTTAACAACAAGGGCTGGCATGCCCTGGTCAGCTTCCTGAACGTGGCTCACAACGCCATCTTGCGGGCCAGCCTGCCCAAGGACAGGGACCCGGAAGAATATGGAATCACCGTTATCAGCCAGCCTCTGAACCTGACCAAGGAGCAGCTCTCAGAGATCACAGT
Seq C2 exon
GCTGACTACTTCCATCGATGCCGTGGTTGCCATATGTGTGATTTTCGCCATGTCCTTCGTTCCAGCCAGCTTTGTCCTCTACCTGATCCAGGAGAGAGTGACGAAAGCCAAACATTTGCAGTTTATCAGTGGTGTGAGCCCCACCACCTACTGGATGACCAACTTCCTCTGGGACATT
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000012892-'50-50,'50-49,52-50=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.080 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=PU(14.3=84.0)
A:
PF126982=ABC2_membrane_3=FE(18.7=100)
C2:
PF126982=ABC2_membrane_3=FE(19.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCCTGTCACCAGAGAGTCT
R:
TGTCCCAGAGGAAGTTGGTCA
Band lengths:
251-421
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000568; ELM sequence: LNLTKE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]