DreEX6095547 @ danRer10
Exon Skipping
Gene
ENSDARG00000057169 | abca4a
Description
ATP-binding cassette, sub-family A (ABC1), member 4a [Source:ZFIN;Acc:ZDB-GENE-050517-3]
Coordinates
chr24:28551782-28552390:+
Coord C1 exon
chr24:28551782-28551856
Coord A exon
chr24:28551946-28552115
Coord C2 exon
chr24:28552213-28552390
Length
170 bp
Sequences
Splice sites
3' ss Seq
CCATTTGTTATCTCCTGTAGGTC
3' ss Score
10.87
5' ss Seq
AGTGTGAGT
5' ss Score
6.96
Exon sequences
Seq C1 exon
GGCAGATACTCAAAGCTTGCTCTGGACGAGTTTGCCACATTTCTGAGGTACATGGAGACTGAAAACAATGTCAAG
Seq A exon
GTCTGGTTCAATAACAAAGGCTGGCACGCAATGGTGGCCTTCATGAACGTGGCAAATAACGCAATCCTTCGAGCAAACCTGCCTCCTGGTGTCGATTTAAATGAATACGGCATCACTGCCATCAATCATCCACTAAACCTGACCAAAGAACAGCTGTCCGAGGTCACAGT
Seq C2 exon
TTTGACCACCTCAGTGGATGCAGTGGTTGCCATCAATGTGATTTTCGCCATGTCCTTCGTGCCGGCTGGTTTTGTGCTGTATTTGATCCAGGAGAGGGTGACGCAGGCCAAACATTTGCAGTTTGTGAGCGGCGTCAGTCCTCTGGTGTACTGGACTGCAAACTTCTTTTGGGACATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000057169-'41-42,'41-41,42-42=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(6.9=100)
A:
PF126982=ABC2_membrane_3=FE(16.0=100)
C2:
PF126982=ABC2_membrane_3=FE(16.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCAAAGCTTGCTCTGGACG
R:
TCCCAAAAGAAGTTTGCAGTCCA
Band lengths:
242-412
Functional annotations
There are 1 annotated functions for this event
PMID: 11320094
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: not specified. ELM ID: ELMI000568; ELM sequence: LNLTKE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]